Routine Immediate Eye Examination at the Point of Care for Diagnosis of AIDS-Related Cytomegalovirus Retinitis Among Patients With a CD4 Count <100 in Myanmar.

Win Le Shwe Sin Ei, Kyi Pyar Soe, Adelene Hilbig, Jillian Murray, David Heiden

Open access · goldAbstract read

In one paragraph

Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.5field-weighted citation impact, top 33% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

Treating HIV-associated cytomegalovirus retinitis with oral valganciclovir and intra-ocular ganciclovir by primary HIV clinicians in southern Myanmar: a retrospective analysis of routinely collected data.BMC infectious diseases · 2020
Article
Clinical Features of Cytomegalovirus Retinitis in HIV Infected Patients.Frontiers in cellular and infection microbiology · 2020
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Win Le Shwe Sin EiMSFCH, Yangon, Myanmar Mission, Myanmar.

Kyi Pyar SoeMSFCH, Dawei, Myanmar Mission, Myanmar.

Adelene HilbigMedecins Sans Frontieres, Geneva, Switzerland.

Jillian MurrayMedecins Sans Frontieres, Geneva, Switzerland.

David HeidenPacific Eye Associates, California Pacific Medical Center Department of Ophthalmology, San Francisco, California; Seva Foundation, Berkeley, California.

Médecins Sans Frontières · CHMyanmar Oxford Clinical Research Unit · MMSeva Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A retrospective review of diagnosis of cytomegalovirus retinitis (CMVR) before and after introduction of routine immediate eye examination among AIDS patients in Myanmar with an absolute CD4 T-cell count <100 cells/μL demonstrated an increased detection of CMVR from 1.1% (14/1233) to 10.7% (65/608), an improvement of ~10-fold. Diagnosis of CMVR was achieved a mean of 2 days after clinic enrollment.

Indexed as

AIDS-related opportunistic infectionsCMV retinitisearly diagnosis of CMV retinitisindirect ophthalmoscopy by nonophthalmologists

Identifiers

PMID31304189

DOI10.1093/ofid/ofz280

PMCPMC6612804

OpenAlexW2952094246

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.