Evidence map›Paper›PMID 31304082›Full record

ArticlePreventive medicine reports2019

Relevance of heat stress and dehydration to chronic kidney disease (CKDu) in Sri Lanka.

K B Jayasekara, P N Kulasooriya, K N Wijayasiri, E D Rajapakse, D S Dulshika, Palitha Bandara, L F Fried, A De Silva, S M Albert

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Preventive medicine reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

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  14. Recent ambient temperature and fine particulate matter (PMThe Science of the total environment · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

K B JayasekaraDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Sir John Kotelawala Defense University, Sri Lanka.
P N KulasooriyaDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Sir John Kotelawala Defense University, Sri Lanka.
K N WijayasiriDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Sir John Kotelawala Defense University, Sri Lanka.
E D RajapakseDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Sir John Kotelawala Defense University, Sri Lanka.
D S DulshikaDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Sir John Kotelawala Defense University, Sri Lanka.
Palitha BandaraProvincial Director's Office of Health, North Central Province, Anuradhapura, Sri Lanka.
L F FriedDivision of Renal-Electrolyte, School of Medicine, University of Pittsburgh and VA Pittsburgh Healthcare System, USA.
A De SilvaDepartment of Behavioral and Community Health Sciences, Graduate School of Public Health, University of Pittsburgh, USA.
S M AlbertDepartment of Behavioral and Community Health Sciences, Graduate School of Public Health, University of Pittsburgh, USA.
General Sir John Kotelawala Defence University · LKUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease in the absence of hypertension and diabetes is a growing problem among agricultural laborers in tropical and subtropical regions. It is unclear if heat stress and dehydration are risk factors for this form of chronic kidney disease (CKDu). To investigate this relationship, agricultural workers in four villages (n = 261) in North Central Province, Sri Lanka completed the US National Institute for Occupational Safety and Health (NIOSH) health hazard evaluation of heat stress, translated into Sinhalese (July 2017). We constructed a heat stress/dehydration index based on the frequency of 16 symptoms (range 0-32; reliability, 0.84). Workers provided a urine sample for dipstick assessment of urine albumin-creatinine ratio (ACR) and refractometer analysis of urine concentration. Of 261 respondents, 41 participants reported diabetes or chronic kidney disease. They scored higher on the heat stress-dehydration index (10.78 vs. 8.03, p < .01) and were more likely to have ACR > 30 (85.4% vs. 69.4%, p < .05). Among 216 non-pregnant agricultural workers without diabetes or kidney disease (mean age, 46.6; 37% male), villagers in the high-CKDu prevalence area were more likely to show signs of dehydration (for example, greater urine concentration, 1.015 vs. 1.012, p < .05, among males); however, the heat stress-dehydration index overall was not associated with ACR or urine concentration. Because an elevated ACR (proteinuria) is not a reliable marker of early CKDu, additional studies are needed to assess the association between heat stress-dehydration symptoms and risk of CKDu.

Indexed as

AgricultureChronic kidney diseaseDehydrationHeat stressSri Lanka

Identifiers

PMID31304082
PMCPMC6603435
OpenAlexW2953028080

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.