Evidence map›Paper›PMID 31304019›Full record

ArticleBasic and clinical andrology2019

Metabolic syndrome and smoking are independent risk factors of male idiopathic infertility.

Charlotte Dupont, Céline Faure, Frederic Daoud, Benoit Gautier, Sébastien Czernichow, Rachel Lévy, ALIFERT collaborative group

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Basic and clinical andrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01093378 (Impact of the Diet Fertility), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01093378 completednot on this map

Impact of the Diet Fertility : A Case-control Multicentric Study

TypeobservationalSponsorAssistance Publique - Hôpitaux de ParisRan2009 to 2015Enrolled400ConditionsInfertility
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Metabolic syndrome and male fertility disorders: Is there a causal link?Reviews in endocrine & metabolic disorders · 2021
    Review
  8. Review
  9. Article
  10. Metabolic Syndrome and Reproduction.International journal of molecular sciences · 2021
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Charlotte Dupont *1Sorbonne Université, Saint Antoine Research center, INSERM équipe Lipodystrophies génétiques et acquisesService de biologie de la reproduction-CECOS, AP-H, Hôpital Tenon, 4 rue de la Chine, 75020 Paris, France.
Céline Faure *AP-HP, Hôpital Tenon, service de biologie de la reproduction CECOS, Paris, France.
Frederic DaoudAP-HP, Hôpital Tenon, service de biologie de la reproduction CECOS, Paris, France.
Benoit GautierAP-HP, Hôpital Tenon, service de biologie de la reproduction CECOS, Paris, France.
Sébastien Czernichow3Université Paris Descartes, Paris, France.
Rachel Lévy1Sorbonne Université, Saint Antoine Research center, INSERM équipe Lipodystrophies génétiques et acquisesService de biologie de la reproduction-CECOS, AP-H, Hôpital Tenon, 4 rue de la Chine, 75020 Paris, France.
ALIFERT collaborative group
Sorbonne Université · FRDélégation Paris 5 · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOverweight and obesity are known to impact male fertility and are commonly associated with abdominal obesity and metabolic disorders. The association between abdominal obesity or metabolic syndrome with male reproduction has not been fully investigated. Moreover, many factors may interfere with the evaluation of the impact of metabolic syndrome on male fertility. Thus, tobacco is known to alter the spermatic parameters and phenomena linking smoking with metabolic syndrome are therefore complex. The main objective of this study has been to investigate the potential association of metabolic syndrome with male idiopathic infertility given smoking status. MATERIEL AND

methodsThe data of this study concerned infertile (

resultsThe present study reports that infertile men are in poorer health condition compared to fertile men and are more often smokers. The results of this study suggested metabolic syndrome and smoking to be independent risk factor for idiopathic infertility.

conclusionsMetabolic syndrome and smoking should systematically be checked at the beginning of medical care in infertile males and personal and multifaceted coaching should be proposed to deal jointly with smoking and metabolic disorders.

trial registrationNCT01093378 ALIFERT. Registered: March 25, 2010.

Indexed as

Male fertilityMetabolic syndromeSmoking

Identifiers

PMID31304019
PMCPMC6600889
OpenAlexW2953625930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.