ArticlePolymer chemistry2019
Site-specific conjugation of antifreeze proteins onto polymer-stabilized nanoparticles.
Article in Polymer chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- DNA-Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Inhibition of Ice Recrystallization by Regulating the Surface Free Energy of Nanoparticles.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Core-block engineering enables control of ice recrystallisation inhibition in polymer nanoparticles.Chemical science · 2026Article
- Generating Ice-Binding Protein-Polymer Bioconjugates.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Controlled Synthesis of Platinum and Silver Nanoparticles Using Multivalent Ligands.Nanomaterials (Basel, Switzerland) · 2022Article
- Polymer Self-Assembly Induced Enhancement of Ice Recrystallization Inhibition.Journal of the American Chemical Society · 2021Article
- Synergistic Ice Inhibition Effect Enhances Rapid Freezing Cryopreservation with Low Concentration of Cryoprotectants.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Ice recrystallisation inhibiting polymer nano-objectsMaterials horizons · 2020Article
- Article
- Ice Binding Proteins: Diverse Biological Roles and Applications in Different Types of Industry.Biomolecules · 2020Review
- Extracellular Antifreeze Protein Significantly Enhances the Cryopreservation of Cell Monolayers.Biomacromolecules · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antifreeze proteins (AFPs) have many potential applications, ranging from cryobiology to aerospace, if they can be incorporated into materials. Here, a range of engineered AFP mutants were prepared and site-specifically conjugated onto RAFT polymer-stabilized gold nanoparticles to generate new hybrid multivalent ice growth inhibitors. Only the SNAP-tagged AFPs lead to potent 'antifreeze' active nanomaterials with His-Tag capture resulting in no activity, showing the mode of conjugation is essential. This versatile strategy will enable the development of multivalent AFPs for translational and fundamental studies.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.