Evidence map›Paper›PMID 31303750›Full record

Trial reportClinical interventions in aging2019

Effect of 12-week home-based cognitive training on cognitive function and brain metabolism in patients with amnestic mild cognitive impairment.

Jinse Park, Si-Eun Kim, Eun-Joo Kim, Byung In Lee, Jee Hyang Jeong, Hae Ri Na, Seong Hye Choi, Do-Young Kang, Kyung Won Park

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Jinse ParkDepartment of Neurology, Haueundae Paik Hospital, Inje University, Busan, South Korea.
Si-Eun KimDepartment of Neurology, Haueundae Paik Hospital, Inje University, Busan, South Korea.
Eun-Joo KimDepartment of Neurology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Busan, South Korea.
Byung In LeeDepartment of Neurology, Haueundae Paik Hospital, Inje University, Busan, South Korea.
Jee Hyang JeongDepartment of Neurology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, South Korea.
Hae Ri NaDepartment of Neurology, Bobath Memorial Hospital, Seongnam, South Korea.
Seong Hye ChoiDepartment of Neurology, Inha University School of Medicine, Incheon, South Korea.
Do-Young KangDepartment of Nuclear Medicine, College of Medicine, Dong-A University, Busan, South Korea.
Kyung Won ParkDepartment of Neurology, Cognitive Disorders and Dementia Center, Dong-A University College of Medicine and Institute of Convergence Bio-Health, Busan, South Korea.
Inje University Haeundae Paik Hospital · KRDong-A University · KRBobath memorial hospital · KREwha Womans University · KRInha University · KRPusan National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe assessed the effect of home-based cognitive intervention (HCI) on cognitive function along with brain metabolism by 18F-FDG PET in patients with amnestic MCI (aMCI). PATIENTS AND

methodsFifty-seven patients with aMCI from three hospitals were randomized (30 HCI, 27 control). For 12 weeks, subjects received HCI. Thirty-two subjects (15 HCI, 17 control) underwent brain 18-F-FDG-PET imaging at baseline and at 12 and 24 weeks.

resultsThe HCI group showed significant improvement in the scores of the Controlled Oral Word Association Test (COWAT) 12 and at 24 weeks. Significant brain metabolic changes by 18F-FDG PET were not observed.

conclusionThe current study suggests that HCI was effective in improving general cognition along with frontal executive function in patients with aMCI.

Indexed as

CognitionAgedBrainCognitive Behavioral TherapyCognitive DysfunctionExecutive FunctionFemaleHumansMaleMiddle AgedNeuropsychological TestsPositron-Emission TomographyTreatment Outcomebrain PETcognitive trainingmild cognitive impairment

Identifiers

PMID31303750
PMCPMC6610290
OpenAlexW2955358824

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.