Evidence map›Paper›PMID 31303706›Full record

ArticleJournal of anaesthesiology, clinical pharmacology

A randomized study to compare palonosetron with ondansetron for prevention of postoperative nausea and vomiting following middle ear surgeries.

Shubhangi Sharma, Sangeeta Khanna, Jyotirmoy Das, Yatin Mehta, Kumud Kumar Handa

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shubhangi SharmaDepartment of ENT and Head and Neck Surgery, Medanta the Medicity Hospital, Gurugram, Haryana, India.
Sangeeta KhannaDepartment of ENT and Head and Neck Surgery, Medanta the Medicity Hospital, Gurugram, Haryana, India.
Jyotirmoy DasDepartment of ENT and Head and Neck Surgery, Medanta the Medicity Hospital, Gurugram, Haryana, India.
Yatin MehtaDepartment of ENT and Head and Neck Surgery, Medanta the Medicity Hospital, Gurugram, Haryana, India.
Kumud Kumar HandaDepartment of ENT and Head and Neck Surgery, Medanta the Medicity Hospital, Gurugram, Haryana, India.
Medanta The Medicity · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsPostoperative nausea and vomiting (PONV) has multifactorial etiology. It is a commonly encountered morbidity after anesthesia specially following middle ear surgery. Various antiemetic medications have been tried with mixed responses. Palonosetron is a newer 5-hydroxytryptamine (5-HT MATERIAL AND

methodsOne hundred patients of ASA class 1 or 2, aged 18 years and above, weighing between 40 and 90 kg scheduled for elective middle ear surgeries were randomly assigned into palonosetron group (

resultsThe incidence of PONV (

conclusionPalonosetron was found to be superior to ondansetron up to 12 hours after the surgery with no significant effect on QTc interval.

Indexed as

Middle ear surgeryondansetronpalonosetronpostoperative nausea and vomiting

Identifiers

PMID31303706
PMCPMC6598573
OpenAlexW2953866411

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.