Evidence map›Paper›PMID 31303681›Full record

ArticleThe Journal of the Oklahoma State Medical Association2018

Overview of Pediatric Nonalcoholic Fatty Liver Disease: A Guide for General Practitioners.

Asiya K Shakir, Upma Suneja, Kevin R Short, Sirish Palle

Abstract read
In one paragraph

Article in The Journal of the Oklahoma State Medical Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Asiya K ShakirUniversity of Oklahoma, Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition.
Upma SunejaUniversity of Oklahoma, Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition.
Kevin R ShortUniversity of Oklahoma Health Sciences Center, Department of Pediatrics, Section of Diabetes and Endocrinology.
Sirish PalleUniversity of Oklahoma, Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition.

Funding

Tracking and Evaluation CoreU54GM104938 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Robert Hal Scofield · 2013 to 2026
$68.2M
The Oklahoma Pediatric Clinical Trials NetworkUG1OD024950 · OD · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Amanda L Bogie, Jeanie Beatrice Tryggestad · 2016 to 2026
$4.1M
NIGMS NIH HHS U54 GM104938NIH HHS UG1 OD024950
6 · The paper itself

Abstract

importanceNonalcoholic fatty liver disease (NAFLD) is rapidly evolving into one of the most common pediatric liver diseases and currently is the most common cause for liver transplantation in young adults. Therefore, early recognition of risk factors, disease prevention, and diagnosis during childhood is paramount for effective management.

objectiveThe primary objective of this review is to discuss updated recommendations for screening, diagnosis and management of NAFLD. The secondary objective is to review the extent and impact of pediatric NAFLD in Oklahoma through our center's participation in a multi-center prospective study. EVIDENCE REVIEW: We reviewed updated guidelines from the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN), the approach used in our clinic and data from a multi-center collaboration on NAFLD, known as TARGET-NASH.

findingsOur review highlights that obese and Hispanic children are at greatest risk for developing NAFLD. Screening with ALT should be considered between ages 9-11 years for children with BMI more than the 95 CONCLUSION AND RELEVANCE: All obese children, especially those who are Hispanics or have a family history of NAFLD should be considered for screening with serum ALT between the ages of 9 and 11 years. Children with ALT values that are elevated more than twice the upper limit of normal for more than 3 months must be referred to pediatric hepatology for timely evaluation.

Indexed as

LiverNAFLDObesityOklahomaPediatric

Identifiers

PMID31303681
PMCPMC6625810

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.