ReviewJournal of cardiology2019
Use of speckle tracking to assess heart failure with preserved ejection fraction.
Review in Journal of cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Usefulness of Strain Echocardiography in Heart Failure with Preserved Ejection Fraction.Journal of clinical medicine · 2026Review
- Coronary microvascular dysfunction in HFpEF: pathophysiologic mechanisms, diagnosis, treatments, and the amplifying potential of sepsis.Frontiers in medicine · 2026Review
- Determinants and Clinical Impact of Visit-to-visit Blood Pressure Variability in Patients with Heart Failure with Preserved Ejection Fraction.JMA journal · 2025Article
- The Clinical Value of Apolipoprotein C3 Combined with FAR and RWT in Heart Failure with Preserved Ejection Fraction.International journal of general medicine · 2025Article
- Diagnostic Value of Two-Dimensional Speckle Tracking Echocardiography in Assessing Cardiac Function in Elderly Patients with Hypertensive Heart Disease.Clinical interventions in aging · 2025Article
- Assessment of cardiac adverse events following COVID-19 vaccination by speckle tracking echocardiography.Scientific reports · 2024Article
- Left ventricular systolic function assessed by standard and advanced echocardiographic techniques in patients with systemic lupus erythematosus: A systemic review and meta-analysis.Archives of rheumatology · 2024Review
- Oxygen venous saturation is associated with subclinical myocardial systolic dysfunction in patients with end-stage renal disease undergoing hemodialysis.Archives of medical sciences. Atherosclerotic diseases · 2024Article
- Review
- The prevalence of abnormal right ventricle speckle strain in the setting of acute myocarditis and preserved left ventricle function.The international journal of cardiovascular imaging · 2023Article
- Heart failure with preserved ejection fraction in post myocardial infarction patients: a myocardial magnetic resonance (MR) tissue tracking study.Quantitative imaging in medicine and surgery · 2023Article
- Clinical Utility of Three-Dimensional Speckle-Tracking Echocardiography in Heart Failure.Journal of clinical medicine · 2022Review
- Differentially expressed TUG1 and miR-145-5p indicate different severity of chronic heart failure and predict 2-year survival prognosis.Experimental and therapeutic medicine · 2021Article
- Improving characterization of hypertrophy-induced murine cardiac dysfunction using four-dimensional ultrasound-derived strain mapping.American journal of physiology. Heart and circulatory physiology · 2021Article
- Speckle Tracking Analysis Reveals Altered Left Atrial and Ventricular Myocardial Deformation in Patients with End-Stage Liver Disease.Journal of clinical medicine · 2021Article
- Circulating Galectin-3 Evaluation in Dogs With Cardiac and Non-cardiac Diseases.Frontiers in veterinary science · 2021Article
- Impact of left atrial appendage occlusion on left atrial function-The LAFIT Watchman study.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Heart failure with preserved ejection fraction (HFpEF) currently represents approximately 50% of heart failure (HF) cases in the USA and is increasingly recognized as a leading cause of morbidity and mortality. Recent data suggest that the prevalence of HFpEF relative to HF with reduced ejection fraction (HFrEF) is increasing at a rate of 1% per year. With an aging population and increasing risk factors such as hypertension, obesity, and diabetes mellitus, HFpEF will soon be the most prevalent HF phenotype. Two-dimensional speckle-tracking echocardiography (STE) has been used to diagnose HFpEF specifically by focusing on the longitudinal systolic function of the left ventricle (LV). Yet there are many patients with HFpEF in whom there are no differences in LV global longitudinal systolic strain, but there are changes in left atrial function and structure. There are several proposed pathophysiological mechanisms for HFpEF such as endothelial dysfunction, interactions among proteins, signaling pathways, and myocardial bioenergetics. Yet only one specific therapy, mineralocorticoid receptor antagonist, spironolactone, is recommended as a treatment for patients with HFpEF. However, spironolactone does not address many of the pathophysiologic changes that occur in HFpEF, thus new novel therapeutic agents are needed. With the limited available therapies, clinicians should use STE to assess for the presence of this syndrome in their patients to provide effective diagnosis and management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.