Evidence map›Paper›PMID 31303249›Full record

ArticleBiophysical journal2019

Cholesterol-Induced Conformational Change in the Sphingomyelin Headgroup.

Shinya Hanashima, Kazuhiro Murakami, Michihiro Yura, Yo Yano, Yuichi Umegawa, Hiroshi Tsuchikawa, Nobuaki Matsumori, Sangjae Seo, Wataru Shinoda, Michio Murata

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Sea Anemones, Actinoporins, and Cholesterol.International journal of molecular sciences · 2022
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Shinya HanashimaDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan. Electronic address: hanashimas13@chem.sci.osaka-u.ac.jp.
Kazuhiro MurakamiDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan.
Michihiro YuraDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan.
Yo YanoDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan.
Yuichi UmegawaDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan; ERATO Lipid Active Structure Project, Japan Science and Technology Agency, Graduate School of Science, Osaka University, Osaka, Japan.
Hiroshi TsuchikawaDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan.
Nobuaki MatsumoriDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan; Department of Chemistry, Graduate School of Science, Kyushu University, Fukuoka, Japan.
Sangjae SeoDepartment of Materials Chemistry, Nagoya University, Nagoya, Japan.
Wataru ShinodaDepartment of Materials Chemistry, Nagoya University, Nagoya, Japan.
Michio MurataDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan; ERATO Lipid Active Structure Project, Japan Science and Technology Agency, Graduate School of Science, Osaka University, Osaka, Japan. Electronic address: murata@chem.sci.osaka-u.ac.jp.
The University of Osaka · JPJapan Science and Technology Agency · JPNagoya University · JPKyushu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sphingomyelin (SM) and cholesterol (Cho) are the important lipids for the formation of biologically functional membrane domains, lipid rafts. However, the interaction between Cho and the headgroup of SM remains unclear. In this study, we performed solid-state NMR experiments to reveal the Cho effects on the headgroup conformation using

Indexed as

Molecular ConformationCholesterolCholineDeuteriumMagnetic Resonance SpectroscopyMolecular Dynamics SimulationProbabilitySphingomyelinsStearic AcidsTemperatureCholesterolCholineDeuteriumSphingomyelinsstearic acidStearic Acids

Identifiers

PMID31303249
PMCPMC6701000
OpenAlexW2955097346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.