Evidence map›Paper›PMID 31303182›Full record

ReviewParasitology2019

J P Dubey, S Almeria

Abstract readReview
PubMed Publisher
In one paragraph

Review in Parasitology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Microscopic and Molecular Identification ofTropical medicine and infectious disease · 2023
    Article
  8. Cystoisospora belli: A Cause of Chronic Diarrhea in Immunocompromised Patients.The American journal of tropical medicine and hygiene · 2023
    Article
  9. Intestinal Parasitic Infections in 2023.Gastroenterology research · 2023
    Review
  10. Development of a new multiplex PCR to detect fecal coccidian parasite.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Article
  11. Article
  12. Review
  13. Life Cycle and Transmission ofMicroorganisms · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Molecular detection of Cystoisospora belli by single-run polymerase chain reaction in stool samples.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021
    Article
  18. Article
  19. Prolonged Severe Watery Diarrhea in a Long-Term Myeloma Survivor: An Unforeseen Infection withTurkish journal of haematology : official journal of Turkish Society of Haematology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

J P DubeyUnited States Department of Agriculture, Agricultural Research Service, Beltsville Agricultural Research Service, Animal Parasitic Disease Laboratory, Building 1001, BARC-East, Beltsville, MD 20705-2350, USA.ORCID 0000-0003-4455-2870
S AlmeriaDepartmentof Health and Human Services, Food and Drug Administration, Center for Food Safety and Nutrition, Office of Applied Research and Safety Assessment, Division of Virulence Assessment, Laurel, MD 20708, USA.
Agricultural Research Service · USCenter for Food Safety and Applied Nutrition · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystoisospora belli is a coccidian parasite of humans, with a direct fecal-oral transmission cycle. It is globally distributed, but mainly found in tropical and subtropical areas. Many cases of C. belli infections have been reported in patients with HIV, and in patients undergoing immunosuppressive therapy for organ transplants or those treated for tumours worldwide. Unsporulated or partially sporulated oocysts of C. belli are excreted in feces. When sporulated oocysts in contaminated water or food are ingested, asexual and sexual stages of C. belli are confined to the epithelium of intestines, bile ducts and gallbladder. Monozoic tissue cysts are present in extra-intestinal organs (lamina propria of the small and large intestine, lymph nodes, spleen, and liver) of immunosuppressed humans. However, a paratenic host has not been demonstrated. Cystoisospora belli infections can be persistent, lasting for months, and relapses are common; the mechanism of relapse is unknown. Recently, the endogenous stages of C. belli were re-examined and attention was drawn to cases of misidentification of non-protozoal structures in the gallbladder of patients as C. belli. Here, we review all aspects of the biology of C. belli, including morphology, endogenous stages, prevalence, epidemiology, symptoms, diagnosis and control.

Indexed as

CoccidiosisSarcocystidaeHumansLife History TraitsPrevalenceCycleCystoisospora bellidiagnosisdistributionhumanssymptomstreatment

Identifiers

PMID31303182
OpenAlexW2959436392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.