Evidence map›Paper›PMID 31303100›Full record

SynthesisJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses

Evidence-Based Recommendations for the Appropriate Level of Sedation to Manage Pain in Pediatric Oncology Patients Requiring Procedures: A Systematic Review From the Children's Oncology Group.

Elizabeth A Duffy, Tara Adams, Clifton P Thornton, Beth Fisher, Jennifer Misasi, Sally McCollum

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Identifying clinical practice guidelines for symptom control in pediatric oncology.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Elizabeth A DuffyThe University of Michigan School of Nursing, Ann Arbor, MI, USA.ORCID 0000-0001-5038-803X
Tara AdamsDell Children's Medical Center, Austin, TX, USA.
Clifton P ThorntonJohns Hopkins School of Nursing, Baltimore MD, USA.
Beth FisherAflac Cancer and Blood Disorder Center, Atlanta, GA, USA.
Jennifer MisasiRush University Medical Center, Chicago, IL, USA.
Sally McCollumDuke University School of Medicine, Durham, NC, USA.
Dell Children's Medical Center of Central Texas · USDuke University · USJohns Hopkins University · USPrisma Health · USRush University Medical Center · USUniversity of Michigan · US

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899
6 · The paper itself

Abstract

Repeated invasive and painful procedures are often necessary components of pediatric cancer treatment. Adequate pain control during procedures is essential; however, procedure-related pain may be underestimated and undertreated. Currently, there is not a standard approach for the appropriate level of sedation to manage procedure-related pain in children with cancer. A team was assembled to review the evidence and develop recommendations to determine the appropriate level of sedation necessary for pain control in patients undergoing pediatric oncology procedures. After a systematic search of the literature, 15 research-based articles were synthesized and critically appraised. A recommendation was made related to the level of sedation utilized for bone marrow aspirates and bone marrow biopsies. There is a need for further research related to the necessary level of sedation for patients undergoing pediatric oncology procedures.

Indexed as

AdolescentCancer PainChildChild, PreschoolEvidence-Based MedicineFemaleHumansInfantInfant, NewbornMaleMedical OncologyNeoplasmsPain ManagementPediatricsPractice Guidelines as TopicProcedural Sedationcancerpainpediatricproceduresedation

Identifiers

PMID31303100
PMCPMC7492720
OpenAlexW2962548016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.