Evidence map›Paper›PMID 31302886›Full record

ArticleEndocrine2019

Trabecular bone score: a useful clinical tool for the evaluation of skeletal health in women of short stature.

Pedro Paulo Martins Alvarenga, Barbara Campolina Silva, Mariana Picoli Diniz, Milena Bellei Leite, Caroline Alves Moreira da Silva, Jessica de Cássia Mendes Eleutério, Maria Marta Sarquis Soares, John P Bilezikian, Bruno Muzzi Camargos

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Article in Endocrine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Update on trabecular bone score.Archives of endocrinology and metabolism · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Pedro Paulo Martins AlvarengaSchool of Medicine, Centro Universitário de Belo Horizonte - UNI-BH, Belo Horizonte, Brazil.
Barbara Campolina SilvaSchool of Medicine, Centro Universitário de Belo Horizonte - UNI-BH, Belo Horizonte, Brazil. barbarasilva2131@gmail.com.ORCID 0000-0001-7276-581X
Mariana Picoli DinizSchool of Medicine, Centro Universitário de Belo Horizonte - UNI-BH, Belo Horizonte, Brazil.
Milena Bellei LeiteSchool of Medicine, Centro Universitário de Belo Horizonte - UNI-BH, Belo Horizonte, Brazil.
Caroline Alves Moreira da SilvaSchool of Medicine, Centro Universitário de Belo Horizonte - UNI-BH, Belo Horizonte, Brazil.
Jessica de Cássia Mendes EleutérioSchool of Medicine, Centro Universitário de Belo Horizonte - UNI-BH, Belo Horizonte, Brazil.
Maria Marta Sarquis SoaresDepartment of Medicine, Federal University of Minas Gerais - UFMG -, Belo Horizonte, Brazil.
John P BilezikianMetabolic Bone Diseases Unit, Division of Endocrinology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Bruno Muzzi CamargosCentro de Densitometria Óssea/Hospital Mater Dei, Belo Horizonte, Brazil.
Centro Universitário de Belo Horizonte · BRUniversidade Federal de Minas Gerais · BRColumbia University · USMater Dei Hospital · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAreal bone mineral density (aBMD) by DXA is underestimated in those with smaller bones and overestimated in those with larger bones. Trabecular bone score (TBS) predicts fracture risk, and is not influenced by bone size. The aim of this study was to evaluate TBS and BMD in women with short stature.

methodsWe retrospectively analyzed DXA scans of all women aged 50-90 years with short stature (<144 cm) obtained in a single center, from 2006 to 2016. The comparison group comprised women >161 cm in height, matched for age and LS BMD, selected from the same database.

resultsThe study population included 342 women. The two groups were similar in age, and aBMD at the LS and total hip. Femoral neck aBMD was lower in cases than in taller women. In contrast, TBS was higher in women with short stature than in their taller counterparts (1.347 ± 0.102 vs. 1.250 ± 0.110; p < 0.001). Bone mineral apparent density (BMAD) and the LS TBS-adjusted BMD T-score were also significantly higher in shorter than in taller women. From the entire cohort, 121 women (67 cases) were osteoporotic by aBMD determinations. Among these subjects, TBS was also greater in cases (1.303 ± 0.103) than in women with standard height (1.190 ± 0.099; p < 0.001). Despite being considered osteoporotic, 36% of short women, but none of the taller ones, had a normal TBS.

conclusionsTBS can be a useful adjunct to aBMD for assessing bone quality in short women, in whom aBMD measurement tends to read lower, and, thus could overestimate fracture risk.

Indexed as

Body HeightAbsorptiometry, PhotonAgedAged, 80 and overBone DensityCancellous BoneFemaleFemur NeckHumansLumbar VertebraeMiddle AgedOsteoporotic FracturesPelvic BonesRetrospective StudiesRisk AssessmentDXAFracture riskOsteoporosisShort statureTrabecular bone score

Identifiers

PMID31302886
OpenAlexW2958603599

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.