Evidence map›Paper›PMID 31302738›Full record

ArticlePediatric radiology2019

Diagnostic yield and safety of ultrasound-guided bowel mass biopsies in children.

Kishore Minhas, Derek J Roebuck, Alex Barnacle, Paolo De Coppi, Neil Sebire, Premal A Patel

Open access · hybridAbstract read
In one paragraph

Article in Pediatric radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Kishore MinhasInterventional Radiology, Radiology Department, Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH, UK.
Derek J RoebuckInterventional Radiology, Radiology Department, Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH, UK.
Alex BarnacleInterventional Radiology, Radiology Department, Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH, UK.
Paolo De CoppiDepartment of Specialist Neonatal and Paediatric Surgery, Great Ormond Street Hospital for Children, London, UK.
Neil SebireDepartment of Pathology, Great Ormond Street Hospital for Children, London, UK.
Premal A PatelInterventional Radiology, Radiology Department, Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH, UK. premalpatel@doctors.org.uk.ORCID http://orcid.org/0000-0003-3504-5092
Great Ormond Street Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraditionally, ultrasound (US)-guided bowel mass biopsies are avoided in favour of endoscopic or surgical biopsies. However, endoscopy cannot easily reach lesions between the duodenojejunal flexure and the terminal ileum and lesions not involving the mucosa may not be accessible via an endoscopic route.

objectiveThe aim of this study was to report our technique and to assess the diagnostic accuracy and safety of US-guided biopsy of bowel masses in children. MATERIALS AND

methodsWe conducted a 14-year retrospective review of US-guided bowel mass biopsies at a single paediatric hospital.

resultsTwenty US-guided bowel mass biopsies were performed in 19 patients (median age: 6 years and 6 months, range: 22 months-17 years, median weight: 22 kg, range: 10.2-48.4 kg). For 14 biopsies, there was no other lesion that could potentially be biopsied. A percutaneous coaxial technique was used for 19 biopsies and a transanal non-coaxial biopsy was performed in 1. A median of 9 (range: 2-15) cores of tissue was obtained at each biopsy. The technical success rate and adequacy of diagnostic yield were 100%. The most common diagnosis was lymphoma, which occurred in 16 biopsies. Three biopsies contained mucosa. There was one complication out of 20 biopsies (5%, 95% confidence interval 0-15%): a self-limiting, post biopsy pyrexia. Nineteen procedures were accompanied by a bone marrow aspirate and/or trephine within 2 weeks of the bowel biopsy, only one of which was diagnostic.

conclusionUS-guided bowel mass biopsy can be performed safely in children, with a high diagnostic yield and low complication rate.

Indexed as

Patient SafetyAdolescentBiopsy, NeedleBurkitt LymphomaChildChild, PreschoolCohort StudiesColonDatabases, FactualFemaleHospitals, PediatricHumansImage-Guided BiopsyImmunohistochemistryInfantLymphoma, B-CellAdolescentsBiopsyBowelChildrenComplication rateDiagnostic yieldLymphomaUltrasound

Identifiers

PMID31302738
PMCPMC6863949
OpenAlexW2956655925

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.