Evidence map›Paper›PMID 31302637›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2020

Total-Body Dynamic Reconstruction and Parametric Imaging on the uEXPLORER.

Xuezhu Zhang, Zhaoheng Xie, Eric Berg, Martin S Judenhofer, Weiping Liu, Tianyi Xu, Yu Ding, Yang Lv, Yun Dong, Zilin Deng and 11 more

3 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 99 papers.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed
19.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04394091 unknown statusnot on this map

Post-treatment Ultrasensitive Positron Emission Tomography in Nasopharyngeal Carcinoma Patients

Typeobservational_patient_registrySponsorSun Yat-sen UniversityRan2020 to 2020Enrolled30ConditionsNasopharyngeal CarcinomaArmsultrasensitive PET CT
NCT04654234 completednot on this map

Total-body PET/CT Imaging Using the uEXPLORER in Non-small Cell Lung Cancer Patients Treated by Induction Chemotherapy Plus Nivolumab and Definitive Concurrent Chemoradiotherapy

Typeobservational_patient_registrySponsorSun Yat-sen UniversityRan2020 to 2023Enrolled15ConditionsNon-small Cell Lung CancerArmsTotal body PET/CT (uExplorer)
NCT04941248 completednot on this mapstarted 2021, after this paper: background citation

The Application of Total-body 13N-NH3 PET/CT to Study the Blood Perfusion System in Severe AS Patients Before and After TAVR Surgery in the Whole Body

TypeobservationalSponsorRenJi HospitalRan2021 to 2026Enrolled34ConditionsCardiac OutputArmstotal-body PET/CT(uEXPLORER , United Imaging Healthcare, China)
3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 206 citations in OpenAlex.

  1. [Abdominal radiology (New York) · 2026
    Article
  2. Review
  3. Discriminating inflammation from malignancy with short-dynamic patlak parametric 18 F-FDG PET/CT.European journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Review
  5. Review
  6. "Pseudo-reference-based Input Function Shape" (pRef-IFS): Towards a True image-derived input function for PET kinetic modeling.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  7. Mitigating bladder signal inEJNMMI physics · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Abbreviated dynamic total-body [Quantitative imaging in medicine and surgery · 2025
    Article
  12. Article
  13. Article
  14. Total-Body Parametric Imaging Using Relative Patlak Plot.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  15. [European journal of nuclear medicine and molecular imaging · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Role of Total Body PET/CT in Inflammatory Disorders.Seminars in nuclear medicine · 2025
    Review
  20. Review

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 2 countries.

Xuezhu ZhangDepartment of Biomedical Engineering, University of California Davis, Davis, California.
Zhaoheng XieDepartment of Biomedical Engineering, University of California Davis, Davis, California.
Eric BergDepartment of Biomedical Engineering, University of California Davis, Davis, California.
Martin S JudenhoferDepartment of Biomedical Engineering, University of California Davis, Davis, California.
Weiping LiuUnited Imaging Healthcare, Shanghai, China.
Tianyi XuUnited Imaging Healthcare, Shanghai, China.
Yu DingUnited Imaging Healthcare, Shanghai, China.
Yang LvUnited Imaging Healthcare, Shanghai, China.
Yun DongUnited Imaging Healthcare, Shanghai, China.
Zilin DengUnited Imaging Healthcare, Shanghai, China.
Songsong TangUnited Imaging Healthcare, Shanghai, China.
Hongcheng ShiZhongshan Hospital, Fudan University, Shanghai, China; and qi@ucdavis.edu.
Pengcheng HuZhongshan Hospital, Fudan University, Shanghai, China; and.
Shuguang ChenZhongshan Hospital, Fudan University, Shanghai, China; and.
Jun BaoUnited Imaging Healthcare, Shanghai, China.
Hongdi LiUnited Imaging Healthcare, Shanghai, China.
Jian ZhouDepartment of Biomedical Engineering, University of California Davis, Davis, California.
Guobao WangDepartment of Radiology, University of California Davis Medical Center, Davis, California.
Simon R CherryDepartment of Biomedical Engineering, University of California Davis, Davis, California.
Ramsey D BadawiDepartment of Biomedical Engineering, University of California Davis, Davis, California.
Jinyi QiDepartment of Biomedical Engineering, University of California Davis, Davis, California qi@ucdavis.edu.
United Imaging Healthcare (China) · CNUniversity of California, Davis · USFudan University · CNUniversity of California Davis Medical Center · USSun Yat-sen University · CN

Funding

EXPLORER: Changing the Molecular Imaging Paradigm with Total Body PETR01CA206187 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BADAWI, RAMSEY D., CHERRY, SIMON R · 2015 to 2019
$15.5M
NCI NIH HHS R01 CA206187
6 · The paper itself

Abstract

The world's first 194-cm-long total-body PET/CT scanner (uEXPLORER) has been built by the EXPLORER Consortium to offer a transformative platform for human molecular imaging in clinical research and health care. Its total-body coverage and ultra-high sensitivity provide opportunities for more accurate tracer kinetic analysis in studies of physiology, biochemistry, and pharmacology. The objective of this study was to demonstrate the capability of total-body parametric imaging and to quantify the improvement in image quality and kinetic parameter estimation by direct and kernel reconstruction of the uEXPLORER data.

Indexed as

Positron Emission Tomography Computed TomographyWhole Body ImagingHumansImage Processing, Computer-Assisteddirect reconstructionkernel methodPETtotal-body parametric imagingtracer kinetics

Identifiers

PMID31302637
PMCPMC8801950
OpenAlexW2959949113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.