Evidence map›Paper›PMID 31302633›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2019

Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second-Generation Amyloid-β Mouse Model.

Christian Sacher, Tanja Blume, Leonie Beyer, Finn Peters, Florian Eckenweber, Carmelo Sgobio, Maximilian Deussing, Nathalie L Albert, Marcus Unterrainer, Simon Lindner and 10 more

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. [Journal of neuroinflammation · 2023
    Article
  6. Article
  7. Review
  8. Review
  9. Longitudinal [Biomedicines · 2022
    Article
  10. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  11. Article
  12. Reduced Acquisition Time [Frontiers in medicine · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. TSPO imaging in animal models of brain diseases.European journal of nuclear medicine and molecular imaging · 2021
    Review
  17. Article
  18. Review
  19. Inflaming the Brain with Iron.Antioxidants (Basel, Switzerland) · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Christian SacherDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany.
Tanja BlumeDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany.
Leonie BeyerDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany.
Finn PetersDZNE-German Center for Neurodegenerative Diseases, Munich, Germany.
Florian EckenweberDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany.
Carmelo SgobioDZNE-German Center for Neurodegenerative Diseases, Munich, Germany.
Maximilian DeussingDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany.
Nathalie L AlbertDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany.
Marcus UnterrainerDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany.
Simon LindnerDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany.
Franz-Josef GildehausDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany.
Barbara von Ungern-SternbergDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany.
Irena BrzakNeuroscience, Novartis Institutes for BioMedical Research (NIBR), Basel, Switzerland.
Ulf NeumannNeuroscience, Novartis Institutes for BioMedical Research (NIBR), Basel, Switzerland.
Takashi SaitoLaboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Saitama, Japan.
Takaomi C SaidoLaboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Saitama, Japan.
Peter BartensteinDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany.
Axel RomingerDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany.
Jochen HermsDZNE-German Center for Neurodegenerative Diseases, Munich, Germany.
Matthias BrendelDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich Germany matthias.brendel@med.uni-muenchen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonphysiologic overexpression of amyloid-β (Aβ) precursor protein in common transgenic Aβ mouse models of Alzheimer disease likely hampers their translational potential. The novel

Indexed as

Positron-Emission TomographyAmyloid beta-PeptidesAmyloidosisAnimalsDisease Models, AnimalFemaleLongitudinal StudiesMaleMiceMicrogliaAmyloid beta-PeptidesAlzheimer diseaseAppNL-G-Fmicrogliaspatial learningβ-amyloid

Identifiers

PMID31302633
PMCPMC6894380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.