ArticleHuman brain mapping2019
Audio-visual and olfactory-visual integration in healthy participants and subjects with autism spectrum disorder.
Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Autism Spectrum Disorder and auditory sensory alterations: a systematic review on the integrity of cognitive and neuronal functions related to auditory processing.Journal of neural transmission (Vienna, Austria : 1996) · 2023Pooled it
- The superior temporal asymmetrical pit remains asymmetric in autism spectrum disorder.bioRxiv : the preprint server for biology · 2026Article
- Prediction and Prediction Error in Autism: A Meta-Analysis of Functional Magnetic Resonance Imaging Results.Biological psychiatry global open science · 2026Article
- Associations between symptom severity in autism and functional neuroimaging measures of audiovisual speech perception.NeuroImage. Clinical · 2026Article
- Odor-enhanced Visual Processing in PTSD.NeuroImage · 2025Article
- Abnormal Functional Connectivity of the Primary Sensory Network in Autism Spectrum Disorder: Sex Differences, Early Overdevelopment, and Clinical Significance.Brain and behavior · 2025Article
- Functional activity, functional connectivity and complex network biomarkers of progressive hyposmia Parkinson's disease with no cognitive impairment: evidences from resting-state fMRI study.Frontiers in aging neuroscience · 2024Article
- fNIRS a novel neuroimaging tool to investigate olfaction, olfactory imagery, and crossmodal interactions: a systematic review.Frontiers in neuroscience · 2024Review
- Alterations of Audiovisual Integration in Alzheimer's Disease.Neuroscience bulletin · 2023Review
- Neural Correlates of Audiovisual Speech Processing in Autistic and Non-Autistic Youth.Multisensory research · 2023Article
- TheFrontiers in behavioral neuroscience · 2023Article
- Less is more: Removing a modality of an expected olfactory-visual stimulation enhances brain activation.Human brain mapping · 2022Article
- Translational Magnetic Resonance Imaging in Autism Spectrum Disorder From the Mouse Model to Human.Frontiers in neuroscience · 2022Review
- Dynamic Causal Modeling Self-Connectivity Findings in the Functional Magnetic Resonance Imaging Neuropsychiatric Literature.Frontiers in neuroscience · 2021Review
- Inhibitory Central Amygdala Outputs to Thalamus Control the Gain of Taste Perception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Processing of Real-World, Dynamic Natural Stimuli in Autism is Linked to Corticobasal Function.Autism research : official journal of the International Society for Autism Research · 2020Article
- Prefrontal Responses to Odors in Individuals With Autism Spectrum Disorders: Functional NIRS Measurement Combined With a Fragrance Pulse Ejection System.Frontiers in human neuroscience · 2020Article
- Audio-visual and olfactory-visual integration in healthy participants and subjects with autism spectrum disorder.Human brain mapping · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
The human capacity to integrate sensory signals has been investigated with respect to different sensory modalities. A common denominator of the neural network underlying the integration of sensory clues has yet to be identified. Additionally, brain imaging data from patients with autism spectrum disorder (ASD) do not cover disparities in neuronal sensory processing. In this fMRI study, we compared the underlying neural networks of both olfactory-visual and auditory-visual integration in patients with ASD and a group of matched healthy participants. The aim was to disentangle sensory-specific networks so as to derive a potential (amodal) common source of multisensory integration (MSI) and to investigate differences in brain networks with sensory processing in individuals with ASD. In both groups, similar neural networks were found to be involved in the olfactory-visual and auditory-visual integration processes, including the primary visual cortex, the inferior parietal sulcus (IPS), and the medial and inferior frontal cortices. Amygdala activation was observed specifically during olfactory-visual integration, with superior temporal activation having been seen during auditory-visual integration. A dynamic causal modeling analysis revealed a nonlinear top-down IPS modulation of the connection between the respective primary sensory regions in both experimental conditions and in both groups. Thus, we demonstrate that MSI has shared neural sources across olfactory-visual and audio-visual stimulation in patients and controls. The enhanced recruitment of the IPS to modulate changes between areas is relevant to sensory perception. Our results also indicate that, with respect to MSI processing, adults with ASD do not significantly differ from their healthy counterparts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.