Evidence map›Paper›PMID 31300831›Full record

Trial reportStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2020

Pulmonary function changes following helical tomotherapy in patients with inoperable, locally advanced non-small cell lung cancer.

K Vekens, S Verbanck, C Collen, G Storme, K Barbé, M De Ridder, E Vanderhelst

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

K VekensRespiratory Division, University Hospital UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium. karolien.vekens@uzbrussel.be.
S VerbanckRespiratory Division, University Hospital UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
C CollenDepartment of Radiotherapy, University Hospital UZ Brussel, Brussels, Belgium.
G StormeDepartment of Radiotherapy, University Hospital UZ Brussel, Brussels, Belgium.
K BarbéDepartment of Biostatistics and Medical Informatics, Vrije Universiteit Brussel, Brussels, Belgium.
M De RidderDepartment of Radiotherapy, University Hospital UZ Brussel, Brussels, Belgium.
E VanderhelstRespiratory Division, University Hospital UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Universitair Ziekenhuis Brussel · BEVrije Universiteit Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate alterations in pulmonary function indices after helical tomotherapy and explore potential associations with biologically corrected dosimetric parameters. PATIENTS AND

methodsIn 64 patients with inoperable locally advanced non-small cell lung cancer, pulmonary function tests before and within 6 months after radiotherapy were evaluated retrospectively. In the case of concurrent chemotherapy a total dose of 67.2 Gy was delivered, otherwise 70.5 Gy was provided. In 44 patients, late pulmonary function changes (≥6 months after radiotherapy) could also be assessed.

resultsIn the entire patient group, there were significant declines in forced expiratory volume in 1s (FEV

conclusionsThe decline in pulmonary function indices after helical tomotherapy was of similar magnitude to that observed in studies reporting the effect of conformal radiotherapy on lung function. Diffusion capacity was the parameter showing the largest decrease following radiation therapy as compared to baseline and correlated with gross tumor volume. None of the alterations in pulmonary function tests were associated with the lung volume receiving low-dose radiation.

Indexed as

Radiotherapy, Intensity-ModulatedAgedCarcinoma, Non-Small-Cell LungFemaleForced Expiratory VolumeHumansLungLung NeoplasmsMaleRespiratory Function TestsRetrospective StudiesIMRTInoperable NSCLCLow-dose radiationPulmonary function indicesRadiation damage

Identifiers

PMID31300831
OpenAlexW2961437189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.