Evidence map›Paper›PMID 31300693›Full record

ArticleScientific reports2019

The burden of 14 hr-HPV genotypes in women attending routine cervical cancer screening in 20 states of Mexico: a cross-sectional study.

Abraham Campos-Romero, Karen S Anderson, Adhemar Longatto-Filho, Marco A Luna-Ruiz Esparza, David J Morán-Portela, Javier A Castro-Menéndez, José L Moreno-Camacho, Diana Y Calva-Espinosa, Manuel A Acosta-Alfaro, Freddy A Meynard-Mejía and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Risk Profile of High-grade Cervical Lesions and Cervical Cancer Considering the Combination of Cytology, HPV Genotype, and Age among Women Undergoing Colposcopy.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2023
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  15. Prevalence ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Abraham Campos-RomeroInnovation and Research Department, Salud Digna, Culiacan, 80000, Sinaloa, Mexico.ORCID http://orcid.org/0000-0002-4982-9528
Karen S AndersonCenter for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA.
Adhemar Longatto-FilhoMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.
Marco A Luna-Ruiz EsparzaInnovation and Research Department, Salud Digna, Culiacan, 80000, Sinaloa, Mexico.
David J Morán-PortelaNational Reference Center, Salud Digna, 80300, Culiacan, Sinaloa, Mexico.
Javier A Castro-MenéndezNational Reference Center, Salud Digna, 80300, Culiacan, Sinaloa, Mexico.
José L Moreno-CamachoNational Reference Center, Salud Digna, 80300, Culiacan, Sinaloa, Mexico.
Diana Y Calva-EspinosaClinical Laboratory Department, Salud Digna, Culiacan, 80000, Sinaloa, Mexico.
Manuel A Acosta-AlfaroHospital Angeles, Culiacan, 80020, Sinaloa, Mexico.
Freddy A Meynard-MejíaMedical Sciences Faculty, Universidad Nacional Autonoma de Nicaragua, Managua, Nicaragua.
Marlene Muñoz-GaitánMedical Sciences Faculty, Universidad Nacional Autonoma de Nicaragua, Managua, Nicaragua.
Jonathan Alcántar-FernándezInnovation and Research Department, Salud Digna, Culiacan, 80000, Sinaloa, Mexico. jonathan.alcantar@salud-digna.org.ORCID http://orcid.org/0000-0001-5302-4223

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Mexico, HPV vaccines available immunize against genotypes 16/18 and 16/18/6/11; however, there is limited surveillance about carcinogenic subtypes in different states of the country that allow evaluating the effectiveness of vaccination and cervical cancer screening programs. Here, we report the regional and age-specific prevalence of 14 hr-HPV genotypes as well as their prevalence in abnormal cytology (from ASCUS to cervical cancer) among Mexican women which were undergoing from cervical cancer screening in the Salud Digna clinics in 20 states of the country. This study includes women with social security from the majority of public health institutions (IMSS, ISSSTE, SEMAR, and PEMEX), and women without social security. For cervical cancer screening, we used the SurePath liquid-based cytology and the BD Onclarity HPV Assay. From December 1, 2016, to August 2, 2018, the hr-HPV prevalence among 60,135 women was 24.78%, the most prevalent types were HPV 16 (4.13%), HPV 31 (4.12%) and HPV 51 (3.39%), while HPV 18 (1.70%) was less prevalent among infected women. Interestingly, the genotypes not covered by current vaccines in Mexico were commonly found in precancerous lesions, evidencing their carcinogenic potential, so it is necessary to increase their surveillance and inclusion in cervical cancer screening triage.

Indexed as

AdolescentAdultAgedAged, 80 and overCross-Sectional StudiesEarly Detection of CancerFemaleGenotypeHumansMass ScreeningMexicoMiddle AgedPapillomaviridaePapillomavirus InfectionsPapillomavirus VaccinesRetrospective StudiesPapillomavirus Vaccines

Identifiers

PMID31300693
PMCPMC6626130

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.