Evidence map›Paper›PMID 31300660›Full record

ArticleScientific reports2019

Fracture types affect clinical outcomes of patients managed within the fracture liaison and osteoporosis medication management services.

Chirn-Bin Chang, Rong-Sen Yang, Lo-Yu Chang, Jen-Kuei Peng, Keh-Sung Tsai, Wei-Jia Huang, Tsung-Han Yang, Ding-Cheng Chan

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. One-year outcomes of an osteoporosis liaison services program initiated within a healthcare system.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
  5. How can the orthopedic surgeon ensure optimal vitamin D status in patients operated for an osteoporotic fracture?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chirn-Bin ChangDepartment of Geriatrics and Gerontology, National Taiwan University Hospital, Taipei, Taiwan.ORCID http://orcid.org/0000-0001-9423-7655
Rong-Sen YangDepartment of Orthopaedics, National Taiwan University Hospital, Taipei, Taiwan.
Lo-Yu ChangCollege of Medicine, National Taiwan University, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-6499-939X
Jen-Kuei PengDepartment of Family Medicine, Bei-Hu Branch, National Taiwan University Hospital, Taipei, Taiwan.
Keh-Sung TsaiSuperintendent Office, Far Eastern Polyclinic of Far Eastern Medical Foundation, Taipei, Taiwan.
Wei-Jia HuangDepartment of Geriatrics and Gerontology, National Taiwan University Hospital, Taipei, Taiwan.
Tsung-Han YangDepartment of Orthopaedics, Hsinchu Branch, National Taiwan University Hospital, Hsinchu City, Taiwan.
Ding-Cheng ChanDepartment of Geriatrics and Gerontology, National Taiwan University Hospital, Taipei, Taiwan. doctord6226@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis medication in fragility fracture patients is associated with better outcomes. However, limited studies have investigated whether fracture types affect outcomes among patients undergoing treatment. We performed a secondary data analysis on participants from a fracture liaison service and an osteoporosis medication management service. Participants (n = 974) were regrouped into hip fracture (HF), vertebral fracture (VF), HF + VF, and NO HF/VF groups at baseline. Bivariate and multivariate logistic regressions were performed to identify baseline correlates on one-year mortality, incident refractures, and falls. Baseline characteristics were different among fracture groups. The HF group was oldest, with the lowest body mass index (BMI), lowest FRAX® T-score and had the highest 10-year fracture risk. After intervention, the HF group still had the highest mortality, but the HF + VF group had the highest refracture and incident fall rates. In the multivariate regression analysis, prevalent HF and VF, lower BMI and albumin level, and having chronic kidney disease or cancer were associated with higher mortality rates. HF + VF patients had the highest refracture risk. Prevalent HF and VF, older age and higher BMI, and having cancer or osteoarthritis were associated with a greater fall risk. HF and VF are associated with adverse outcomes, even under an optimal fracture care.

Indexed as

Accidental FallsAgedAgingBody Mass IndexBone DensityBone Density Conservation AgentsFemaleHip FracturesHumansMaleMalnutritionOsteoporosisOsteoporotic FracturesRiskRisk FactorsSpinal FracturesBone Density Conservation Agents

Identifiers

PMID31300660
PMCPMC6626060

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.