Evidence map›Paper›PMID 31300524›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Tetrodotoxin-Sensitive Sodium Channels Mediate Action Potential Firing and Excitability in Menthol-Sensitive Vglut3-Lineage Sensory Neurons.

Theanne N Griffith, Trevor A Docter, Ellen A Lumpkin

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Self-renewal of neuronal mitochondria through asymmetric division.bioRxiv : the preprint server for biology · 2025
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  6. The Electrically Silent Kv5.1 Subunit Forms Heteromeric Kv2 Channels in Cortical Neurons and Confers Distinct Functional Properties.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Article
  8. Article
  9. Ion channels of cold transduction and transmission.The Journal of general physiology · 2024
    Review
  10. Article
  11. KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Article
  13. Article
  14. Intrinsic Homeostatic Plasticity in Mouse and Human Sensory Neurons.bioRxiv : the preprint server for biology · 2023
    Article
  15. Article
  16. NaeLife · 2022
    Article
  17. Article
  18. Low-Threshold Mechanosensitive VGLUT3-Lineage Sensory Neurons Mediate Spinal Inhibition of Itch by Touch.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Theanne N GriffithDepartment of Physiology and Cellular Biophysics.
Trevor A DocterUndergraduate Program in Neuroscience and Behavior.
Ellen A LumpkinDepartment of Physiology and Cellular Biophysics, ellen.a.lumpkin@gmail.com.
Columbia University · USDivision of Undergraduate Education · USMarine Biological Laboratory · US

Funding

Mechanisms of mechanosensory transduction in Merkel cellsR01AR051219 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LUMPKIN, ELLEN A · 2004 to 2020
$6.0M
Training in Cardiovascular Translational ResearchT32HL120826 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARKS, ANDREW ROBERT, TABAS, IRA A · 2014 to 2023
$4.7M
Translational and Precision Medicine Resources Core (TRAP)P30AR069632 · NIAMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHRISTIANO, ANGELA M · 2016 to 2020
$3.9M
Neurobiology Summer CourseR25NS063307 · NINDS · MARINE BIOLOGICAL LABORATORY · PI Ricardo C Araneda, Michael Blake Hoppa · 2008 to 2026
$3.5M
NHLBI NIH HHS T32 HL120826NIAMS NIH HHS P30 AR069632NIAMS NIH HHS R01 AR051219NINDS NIH HHS R25 NS063307
6 · The paper itself

Abstract

Small-diameter vesicular glutamate transporter 3-lineage (Vglut3

Indexed as

Action PotentialsAmino Acid Transport Systems, AcidicAnimalsCells, CulturedFemaleGanglia, SpinalHEK293 CellsHumansMaleMentholMiceMice, Inbred C57BLNAV1.8 Voltage-Gated Sodium ChannelNeurons, AfferentSodium Channel BlockersTetrodotoxinAmino Acid Transport Systems, AcidicMentholNAV1.8 Voltage-Gated Sodium ChannelScn10a protein, mouseSlc17a8 protein, mouseSodium Channel BlockersTetrodotoxinTRPM8 protein, mouseTRPM Cation Channelsaction potentialdorsal root ganglionexcitabilitysensory neuronsodium channel

Identifiers

PMID31300524
PMCPMC6733551
OpenAlexW2957214449

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.