Evidence map›Paper›PMID 31300520›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through

Christopher R Bye, Valeria Rytova, Walaa F Alsanie, Clare L Parish, Lachlan H Thompson

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

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  11. Identification of Novel Genetic Loci Affecting Age at Onset of Parkinson's Disease: A Genome-wide Association Study.Movement disorders : official journal of the Movement Disorder Society · 2025
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  19. L1CAM variants cause two distinct imaging phenotypes on fetal MRI.Annals of clinical and translational neurology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Christopher R ByeFlorey Institute for Neuroscience and Mental Health, The University of Melbourne, Royal Parade, Parkville, Victoria, Australia 3010 chris.bye@florey.edu.au lachlant@unimelb.edu.au.ORCID 0000-0003-1714-5954
Valeria RytovaFlorey Institute for Neuroscience and Mental Health, The University of Melbourne, Royal Parade, Parkville, Victoria, Australia 3010.ORCID 0000-0002-8540-7445
Walaa F AlsanieFlorey Institute for Neuroscience and Mental Health, The University of Melbourne, Royal Parade, Parkville, Victoria, Australia 3010.
Clare L ParishFlorey Institute for Neuroscience and Mental Health, The University of Melbourne, Royal Parade, Parkville, Victoria, Australia 3010.ORCID 0000-0001-8212-9884
Lachlan H ThompsonFlorey Institute for Neuroscience and Mental Health, The University of Melbourne, Royal Parade, Parkville, Victoria, Australia 3010 chris.bye@florey.edu.au lachlant@unimelb.edu.au.ORCID 0000-0003-2632-0304
The University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growth of axons corresponding to different neuronal subtypes is governed by unique expression profiles of molecules on the growth cone. These molecules respond to extracellular cues either locally though cell adhesion interactions or over long distances through diffusible gradients. Here, we report that that the cell adhesion molecule ALCAM (CD166) can act as an extracellular substrate to selectively promote the growth of murine midbrain dopamine (mDA) neuron axons through a

Indexed as

Activated-Leukocyte Cell Adhesion MoleculeAnimalsAntibodies, BlockingAxonsCell Adhesion MoleculesDopaminergic NeuronsFemaleGrowth ConesMaleMesencephalonMiceMice, KnockoutNeural Cell Adhesion Molecule L1SemaphorinsSignal TransductionActivated-Leukocyte Cell Adhesion MoleculeAntibodies, BlockingCell Adhesion MoleculesChl1 protein, mouseNeural Cell Adhesion Molecule L1SemaphorinsCAMsconnectivityguidancemesencephalonNrp1

Identifiers

PMID31300520
PMCPMC6703882
OpenAlexW2958717364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.