Evidence map›Paper›PMID 31300469›Full record

ArticleJournal of investigative medicine : the official publication of the American Federation for Clinical Research2020

Low-grade appendiceal mucinous neoplasms confined to the appendix: clinical manifestations and CT findings.

Xiang-Rong Yu, Jun Mao, Wei Tang, Xiang-Ying Meng, Ye Tian, Zhong-Li Du

Abstract read
In one paragraph

Article in Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  14. [Incidental finding of appendiceal mucinous neoplasms].Chirurgie (Heidelberg, Germany) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiang-Rong YuDepartment of Radiology, Zhuhai Hospital of Jinan University, Zhuhai People's Hospital, Zhuhai, China.
Jun MaoDepartment of Radiology, Zhuhai Hospital of Jinan University, Zhuhai People's Hospital, Zhuhai, China.
Wei TangDepartment of Radiology, Fudan University Shanghai Cancer Center, Shanghai, China.
Xiang-Ying MengDepartment of Pharmaceutics, Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
Ye TianDepartment of Radiology, Zhuhai Hospital of Jinan University, Zhuhai People's Hospital, Zhuhai, China.
Zhong-Li DuDepartment of Radiology, Zhuhai Hospital of Jinan University, Zhuhai People's Hospital, Zhuhai, China.ORCID 0000-0003-1625-1552

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical findings and CT images are investigated in order to fulfill an early preoperative diagnosis and increase awareness of low-grade appendiceal mucinous neoplasm (LAMN) confined to the appendix. 17 cases with histologically proven LAMNs confined to the appendix were included in this study. All patients had received multiphase CT examinations before the surgery. The imaging criteria included shape, size, margin, attenuation, secondary degeneration and internal mass enhancement pattern. In CT images, all cases appeared as oval or tubular cystic masses (average attenuation 20.4±3.6 Hounsfield units), with the longest dimensions ranging from approximately 38 to 106 mm (mean 66.3 mm), and the ratio of length against width was 1.83 in average. The cystic wall was unevenly thickened, with a mean maximal wall thickness of 5.7 mm (>10 mm in 3 cases). The inner capsule wall was rough, and calcification was observed in 3 cases. A few amounts of periappendiceal fat stranding were noted in 2 cases. Mild ring mural enhancement of the cystic wall was seen during the arterial phase, with progressive enhancement during the portal venous phase. In addition, mini enhancing mural nodules was observed in 5 cases. Although preoperative diagnosis of LAMNs confined to the appendix remains challenging, it should be considered when a focal well-defined cystic mass with slightly higher than water attenuation, thickened cystic wall with ring mural enhancement and a characteristic progressive contrast enhancement in CT imaging, especially in older females with non-specific symptoms similar to appendicitis.

Indexed as

Tomography, X-Ray ComputedAdenocarcinoma, MucinousAdultAgedAged, 80 and overAppendiceal NeoplasmsAppendicitisAppendixContrast MediaDiagnosis, DifferentialFemaleHumansMaleMiddle AgedNeoplasm GradingPreoperative CareContrast Mediaappendixcomputed tomographydiagnosislow-grade mucinous neoplasm

Identifiers

PMID31300469
PMCPMC6996116

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.