Evidence map›Paper›PMID 31300419›Full record

ArticleBlood advances2019

Sporadic and endemic Burkitt lymphoma have frequent

Peixun Zhou, Alex E Blain, Alexander M Newman, Masood Zaka, George Chagaluka, Filbert R Adlar, Ugonna T Offor, Casey Broadbent, Lewis Chaytor, Amber Whitehead and 9 more

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Multi-Modal Deep Learning-Based Model to Predict Burkitt Lymphoma Recurrence.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 2 countries.

Peixun ZhouWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0003-2498-5986
Alex E BlainWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0001-8045-822X
Alexander M NewmanWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0002-6733-3833
Masood ZakaWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.
George ChagalukaDepartment of Paediatrics, College of Medicine, Queen Elizabeth Central Hospital, Blantyre, Malawi.
Filbert R AdlarWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.
Ugonna T OfforWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0002-7207-3175
Casey BroadbentWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.
Lewis ChaytorWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.
Amber WhiteheadWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.
Amy HallWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.
Hettie O'ConnorWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.
Susan Van NoordenDepartment of Histopathology, Imperial College London, Hammersmith Hospital, London, United Kingdom.
Irvin LampertDepartment of Histopathology, West Middlesex University Hospital, Isleworth, United Kingdom; and.
Simon BaileyWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.
Elizabeth MolyneuxDepartment of Paediatrics, College of Medicine, Queen Elizabeth Central Hospital, Blantyre, Malawi.ORCID 0000-0001-5479-5900
Chris M BaconWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0002-8268-2812
Simon BomkenWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.
Vikki RandWolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0002-2198-8949
Newcastle University · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GBQueen Elizabeth Central Hospital · MWHammersmith Hospital · GBWest Middlesex University Hospital · GB

Funding

Cancer Research UKMedical Research Council
6 · The paper itself

Abstract

FOXO1 has an oncogenic role in adult germinal center-derived lymphomas, in which mutations, predominately within the AKT recognition motif, cause nuclear retention of FOXO1, resulting in increased cell proliferation. To determine the prevalence and distribution of

Indexed as

Binding SitesMutationNucleotide MotifsAdolescentBurkitt LymphomaChildChild, PreschoolDEAD-box RNA HelicasesDNA-Binding ProteinsFemaleForkhead Box Protein O1Gene FrequencyGene Knockout TechniquesHigh-Throughput Nucleotide SequencingHumansInfantARID1A protein, humanDDX3X protein, humanDEAD-box RNA HelicasesDNA-Binding ProteinsForkhead Box Protein O1FOXO1 protein, humanProto-Oncogene Proteins c-aktTranscription Factors

Identifiers

PMID31300419
PMCPMC6650741
OpenAlexW2957611103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.