ArticleArchives of disease in childhood2020
Neurodevelopment at 2 years corrected age among Vietnamese preterm infants.
Article in Archives of disease in childhood, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- The prevalence of long-term neurodevelopmental outcomes in preterm-born children in low- and middle-income countries: a systematic review and meta-analysis of developmental outcomes in 72 974 preterm-born children.Journal of global health · 2025Pooled it
- Implementation of developmental care in routine NICU practice and early clinical outcomes in preterm infants.Frontiers in pediatrics · 2026Article
- Neonatal respiratory care in Vietnam: surfactant use and clinical practices in a large neonatal intensive care unit.BMC pediatrics · 2025Observational
- Radiomics models predict early neurodevelopment in infants with congenital cardiac septal defects.Quantitative imaging in medicine and surgery · 2025Article
- Article
- Two-Year Longitudinal Motor Performance of Very Preterm and/or Very-Low-Birth-Weight Infants in Suriname.Children (Basel, Switzerland) · 2025Article
- Developmental Trajectories and Differences in Functional Brain Network Properties of Preterm and At-Term Neonates.Human brain mapping · 2025Article
- Neurodevelopmental delay and associated factors among preterm infants aged 6 to 24 months adjusted gestation age in two urban hospitals in Uganda.PLOS global public health · 2025Article
- Machine Learning for the Identification of Key Predictors to Bayley Outcomes: A Preterm Cohort Study.Journal of personalized medicine · 2024Article
- The relationship between neonatal stress in preterm infants and developmental outcomes at the corrected age of 24-30 months.Frontiers in psychology · 2024Article
- Neurodevelopmental outcomes of very low birth weight preterms in preschool childhood: a prospective cohort study.Italian journal of pediatrics · 2023Article
- The H-HOPE behavioral intervention plus Kangaroo Mother Care increases mother-preterm infant responsivity in Malawi: a prospective cohort comparison.BMC pediatrics · 2023Article
- Article
- Risk Factors of Language Delay at Two Years of Corrected Age among Very-Low-Birth-Weight Preterm Infants: A Population-Based Study.Children (Basel, Switzerland) · 2023Article
- Prevalence of Language Delay among Healthy Preterm Children, Language Outcomes and Predictive Factors.Children (Basel, Switzerland) · 2021Article
- Research Trends of Follow-Up Care after Neonatal Intensive Care Unit Graduation for Children Born Preterm: A Scoping Review.International journal of environmental research and public health · 2021Article
- Poor Head Growth Is Associated with Later Mental Delay among Vietnamese Preterm Infants: A Follow-up Study.Journal of tropical pediatrics · 2021Article
- Neurodevelopmental outcomes of preterm babies during infancy in Eastern Uganda: a prospective cohort study.Global health action · 2020Article
- Article
- Neurodevelopmental outcomes of preterm infants: a recent literature review.Translational pediatrics · 2020Article
Corrections and comments
- Commented on by
Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundPreterm infants are at risk of neurodevelopmental delay, but data on long-term outcomes in low-income and middle-income countries remain scarce.
objectivesTo examine neurodevelopment using Bayley Scales of Infant and Toddler Development-3rd edition (Bayley-III) and neurological findings in 2-year-old preterm infants, and to compare with healthy Vietnamese infants. Further, to assess factors associated with neurodevelopmental impairment. DESIGN AND
settingCohort study to follow up preterm infants discharged from a neonatal intensive care unit (NICU) of a tertiary children's hospital in Vietnam.
participantsInfants born at <37 weeks of gestational age. MAIN OUTCOMES: Bayley-III assessment and neurological examination at 2-year corrected age (CA) compared with healthy Vietnamese infants.
resultsOf 294 NICU preterm infants, Bayley-III scores of all 184/243 (76%) survivors at 2 years CA were significantly lower than those of healthy Vietnamese peers in all three domains: cognition (mean (SD): 84.5 (8.6) vs 91.4 (7.5), p<0.001), language (mean (SD): 88.7 (12.5) vs 95.9 (11.9), p<0.001) and motor (mean (SD): 93.1 (9.0) vs 96.8 (9.3), p=0.003). The mean differences in Bayley-III scores between preterm and healthy Vietnamese infants were -6.9 (-9.1 to -4.7), -7.2 (-10.5 to -3.8) and -3.7 (-6.1 to -1.2) for cognitive, language and motor scores, respectively. The prevalence of neurodevelopmental impairment was 17% for cognitive, 8% for language and 4% for motor performance. In total, 7% were diagnosed with cerebral palsy. Higher maternal education was positively associated with infant neurodevelopment (OR 0.32, 95% CI 0.11 to 0.94).
conclusionsVietnamese preterm infants in need of neonatal intensive care showed poor neurodevelopment at 2 years. Higher maternal education was positively associated with infant neurodevelopment. Standard follow-up programmes for preterm infants should be considered in low-resource settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.