Evidence map›Paper›PMID 31299972›Full record

Trial reportRespiratory research2019

Consequences of chronic kidney disease in chronic obstructive pulmonary disease.

Franziska C Trudzinski, Mohamad Alqudrah, Albert Omlor, Stephen Zewinger, Danilo Fliser, Timotheus Speer, Frederik Seiler, Frank Biertz, Armin Koch, Claus Vogelmeier and 7 more

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in Respiratory research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01245933 (Impact of Systemic Manifestations/Comorbidities on Clinical State, Prognosis and Utilisation of Health Care Resources in Patients With COPD), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01245933 completednot on this map

Impact of Systemic Manifestations/Comorbidities on Clinical State, Prognosis and Utilisation of Health Care Resources in Patients With COPD

TypeobservationalSponsorPhilipps University MarburgRan2010 to 2023Enrolled2,741ConditionsChronic Obstructive Pulmonary Disease (COPD)
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Observational
  5. Observational
  6. Article
  7. Soft tissue calcifications in chronic kidney disease-beyond the vasculature.Pflugers Archiv : European journal of physiology · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The Diagnosis and Treatment of COPD and Its Comorbidities.Deutsches Arzteblatt international · 2023
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Franziska C TrudzinskiDepartment of Internal Medicine V - Pulmonology, Allergology Critical Care Care Medicine, Saarland University Hospital, Homburg, Germany.
Mohamad AlqudrahDepartment of Internal Medicine V - Pulmonology, Allergology Critical Care Care Medicine, Saarland University Hospital, Homburg, Germany.
Albert OmlorDepartment of Internal Medicine V - Pulmonology, Allergology Critical Care Care Medicine, Saarland University Hospital, Homburg, Germany.
Stephen ZewingerDepartment of Internal Medicine IV - Nephrology, Saarland University Hospital, Homburg, Germany.
Danilo FliserDepartment of Internal Medicine IV - Nephrology, Saarland University Hospital, Homburg, Germany.
Timotheus SpeerDepartment of Internal Medicine IV - Nephrology, Saarland University Hospital, Homburg, Germany.
Frederik SeilerDepartment of Internal Medicine V - Pulmonology, Allergology Critical Care Care Medicine, Saarland University Hospital, Homburg, Germany.
Frank BiertzInstitute for Biostatistics, Hannover Medical School, Hannover, Germany.
Armin KochInstitute for Biostatistics, Hannover Medical School, Hannover, Germany.
Claus VogelmeierDepartment of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Philipps-University Marburg, Member of the German Center for Lung Research (DZL), Marburg, Germany.
Tobias WelteClinic for Pneumology Hannover Medical School, Member of the German Center for Lung Research, Hannover, Germany.
Henrik WatzPulmonary Research Institute at LungenClinic Grosshansdorf Airway Research Center North, Member of the German Center for Lung Research, Grosshansdorf, Germany.
Benjamin WaschkiPulmonary Research Institute at LungenClinic Grosshansdorf Airway Research Center North, Member of the German Center for Lung Research, Grosshansdorf, Germany.
Sebastian FähndrichDepartment of Internal Medicine V - Pulmonology, Allergology Critical Care Care Medicine, Saarland University Hospital, Homburg, Germany.
Rudolf JörresInstitute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Munich, Germany.
Robert BalsDepartment of Internal Medicine V - Pulmonology, Allergology Critical Care Care Medicine, Saarland University Hospital, Homburg, Germany. robert.bals@uks.eu.
German COSYCONET consortium
Saarland University · DEGerman Center for Lung Research · DEMedizinische Hochschule Hannover · DELungenClinic Grosshansdorf · DE

Funding

Bundesministerium für Bildung und Forschung 01GI0881Bundesministerium für Bildung und Forschung 01GI0882
6 · The paper itself

Abstract

backgroundThe combination of chronic obstructive pulmonary disease (COPD) and chronic kidney disease (CKD) is associated with a higher prevalence of comorbidities and increased mortality. The impact of kidney function on patient-centered outcomes in COPD has not been evaluated.

methodsPatients from the German COPD and Systemic Consequences - Comorbidities Network (COSYCONET) cohort COPD were analysed. CKD was diagnosed if the estimated glomerular filtration rate (eGFR) measurements were < 60 mL/min/1.73m

results2274 patients were analysed, with CKD diagnosed in 161 (7.1%). Spline models adjusted for age, gender, BMI, FEV

conclusionThese data show that CKD is a relevant comorbidity in COPD patients which impacts on patient-centered outcomes and mortality.

trial registrationNCT01245933.

Indexed as

AgedCohort StudiesComorbidityFemaleHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveRenal Insufficiency, ChronicRespiratory Function TestsWalk TestChronic kidney diseaseChronic obstructive pulmonary diseaseCohort studyPatient-centered outcomes

Identifiers

PMID31299972
PMCPMC6626422
OpenAlexW2960027451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.