Evidence map›Paper›PMID 31299860›Full record

ReviewExperimental biology and medicine (Maywood, N.J.)2019

Pathogenic mutations in genes encoding nuclear envelope proteins and defective nucleocytoplasmic connections.

Cecilia Östlund, Wakam Chang, Gregg G Gundersen, Howard J Worman

Abstract readReview
In one paragraph

Review in Experimental biology and medicine (Maywood, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cecilia ÖstlundDepartment of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Wakam ChangDepartment of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Gregg G GundersenDepartment of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Howard J WormanDepartment of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.ORCID 0000-0001-7810-9688

Funding

Pathogenesis of Emery-Dreifuss Muscular DystrophyR01AR048997 · NIAMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WORMAN, HOWARD J · 2003 to 2024
$7.1M
Role of Nucleo-cytoskeleton Interactions in Cell MigrationR01GM099481 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GUNDERSEN, GREGG G · 2011 to 2019
$2.9M
Nuclear Movement LINC Complex and Emery-Dreifuss Muscular DystrophyR01AR068636 · NIAMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GUNDERSEN, GREGG G, WORMAN, HOWARD J · 2015 to 2019
$2.2M
NIAMS NIH HHS R01 AR048997NIAMS NIH HHS R01 AR068636NIGMS NIH HHS R01 GM099481
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell PolarityHumansMembrane ProteinsMutationNuclear EnvelopeNuclear ProteinsMembrane ProteinsNuclear ProteinsLaminlinker of nucleoskeleton and cytoskeleton complex complexnesprinnuclear envelopeSUN protein

Identifiers

PMID31299860
PMCPMC6880145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.