Evidence map›Paper›PMID 31299328›Full record

ArticleUrology2019

Bladder Hydrodistention Does Not Result in a Significant Change in Bladder Capacity for Interstitial Cystitis/Bladder Pain Syndrome Patients.

Stephen J Walker, Andre Plair, Kshipra Hemal, Carl D Langefeld, Catherine Matthews, Gopal Badlani, Joao Zambon, Heather Heath, Robert J Evans

Open access · greenAbstract read
In one paragraph

Article in Urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. [Treatment of intravesical instillation with fulguration-hydrodistention on female interstitial cystitis].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Stephen J WalkerDepartment of Urology/Female Pelvic Health, Wake Forest Baptist Medical Center, Winston-Salem, NC; Wake Forest Institute for Regenerative Medicinske Forest Baptist Medical Center, Winston-Salem, NC. Electronic address: swalker@wakehealth.edu.
Andre PlairDepartment of Urology/Female Pelvic Health, Wake Forest Baptist Medical Center, Winston-Salem, NC.
Kshipra HemalWake Forest University School of Medicine, Winston-Salem, NC.
Carl D LangefeldDepartment of Biostatistics and Data Science, Wake Forest Baptist Medical Center, Winston-Salem, NC.
Catherine MatthewsDepartment of Urology/Female Pelvic Health, Wake Forest Baptist Medical Center, Winston-Salem, NC.
Gopal BadlaniDepartment of Urology/Female Pelvic Health, Wake Forest Baptist Medical Center, Winston-Salem, NC.
Joao ZambonDepartment of Urology/Female Pelvic Health, Wake Forest Baptist Medical Center, Winston-Salem, NC.
Heather HeathWake Forest Institute for Regenerative Medicinske Forest Baptist Medical Center, Winston-Salem, NC.
Robert J EvansDepartment of Urology/Female Pelvic Health, Wake Forest Baptist Medical Center, Winston-Salem, NC.
Atrium Health Wake Forest Baptist · USForest Institute · USWake Forest University · US

Funding

Biomarkers for Molecular-Based Decision-Making in Diagnosis and Treatment of InteR21DK106554 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WALKER, STEPHEN · 2015 to 2016
$426k
NIDDK NIH HHS R21 DK106554
6 · The paper itself

Abstract

objectiveTo assess the impact of multiple (2 or more) bladder hydrodistentions (HODs) on anesthetic bladder capacity (BC) in a large cohort of interstitial cystitis/bladder pain syndrome (IC/BPS) patients. Urinary HOD under anesthesia is a third line therapeutic approach used to treat patients with IC/BPS. There is some concern that performing multiple therapeutic HODs may be contraindicated due to the potential for contributing to a diminished BC over time. MATERIALS AND

methodsThis is a retrospective chart review of IC/BPS patients from a single institution who had undergone 2 or more bladder HOD procedures. Patient demographic and clinical data, including BC under anesthesia, were retrieved from patient charts for analysis. Least squares regression slopes of BC under anesthesia were calculated and used to estimate within-patient BC changes over time.

resultsData from 168 patients (637 HOD procedures) were included for analysis. The average change in BC, 0.52 ± 8.33 mL/mo, was not significantly different from 0 (P= .42). Linear regression analyses did not identify any significant correlation between BC over time with: (1) age, (2) number of HODs, (3) frequency of HODs, (4) average BC, (5) length of time with an IC/BPS diagnosis, or (6) length of time during which the patient's BC was evaluated. Moreover, there was no difference in BC change over time in patients with and without Hunner's lesion (P = .86).

conclusionMultiple therapeutic HODs, over several years, do not result in a significant change in BC in IC/BPS patients.

Indexed as

AnesthesiaPhysical Therapy ModalitiesAdolescentAdultAgedAged, 80 and overCystitis, InterstitialFemaleHumansMaleMiddle AgedRetrospective StudiesUrinary BladderWaterYoung AdultWater

Identifiers

PMID31299328
PMCPMC6778031
OpenAlexW2962496842

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.