Evidence map›Paper›PMID 31299273›Full record

ArticleThe international journal of biochemistry & cell biology2019

Genetically targeted fluorescent probes reveal dynamic calcium responses to adrenergic signaling in multiple cardiomyocyte compartments.

Ivan Luptak, Robert Morgan, Tomas Baka, Dominique Croteau, Daniel Moverman, Hannah Sarnak, Michael Kirber, Markus M Bachschmid, Wilson S Colucci, David R Pimentel

Open access · greenAbstract read
In one paragraph

Article in The international journal of biochemistry & cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Ivan LuptakMyocardial Biology Unit, Boston University School of Medicine, Boston, MA, United States.
Robert MorganMyocardial Biology Unit, Boston University School of Medicine, Boston, MA, United States.
Tomas BakaInstitute of Pathophysiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Dominique CroteauMyocardial Biology Unit, Boston University School of Medicine, Boston, MA, United States.
Daniel MovermanMyocardial Biology Unit, Boston University School of Medicine, Boston, MA, United States.
Hannah SarnakMyocardial Biology Unit, Boston University School of Medicine, Boston, MA, United States.
Michael KirberCellular Imaging Core, Boston University School of Medicine, Boston, MA, United States.
Markus M BachschmidVascular Biology Unit, Boston University School of Medicine, Boston, MA, United States.
Wilson S ColucciMyocardial Biology Unit, Boston University School of Medicine, Boston, MA, United States.
David R PimentelMyocardial Biology Unit, Boston University School of Medicine, Boston, MA, United States. Electronic address: dapiment@bmc.org.
Boston University · USComenius University Bratislava · SK

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
Oxidative Stress in Myocardial Remodeling and FailureR01HL064750 · NHLBI · BOSTON MEDICAL CENTER · PI COLUCCI, WILSON S. · 2001 to 2018
$5.0M
Redox Control of Hepatic Lipid MetabolismR01DK103750 · NIDDK · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BACHSCHMID, MARKUS MICHAEL · 2015 to 2019
$1.8M
Ventricular Remodeling from H202 in Mechanical OverloadK08HL071563 · NHLBI · BOSTON MEDICAL CENTER · PI PIMENTEL, DAVID R · 2005 to 2009
$634k
NHLBI PROTEOMICS INITIATIVE-N01HV28178N01HV028178 · HV · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COSTELLO, CATHERINE E. · 2002 to 2006
–
STRUCTURAL CHARACTERIZATION OF THE APOPROTEIN E RECEPTORR01HL028178 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI INNERARITY, THOMAS L. · 1986 to 1988
–
American Heart Association-American Stroke Association 16GRNT27660006NCATS NIH HHS UL1 TR001430NHLBI NIH HHS K08 HL071563NHLBI NIH HHS N01 HV028178NHLBI NIH HHS R01 HL064750NIDDK NIH HHS R01 DK103750
6 · The paper itself

Abstract

Calcium (Ca

Indexed as

Calcium SignalingFluorescence Resonance Energy TransferAnimalsCalciumFluorescent DyesMaleMyocytes, CardiacRatsRats, Sprague-DawleyReceptors, AdrenergicCalciumFluorescent DyesReceptors, AdrenergicCalcium signalingCameleonCellular compartmentsFRET imagingMitochondrial calciumMitochondrial calcium uniporter dominant negative

Identifiers

PMID31299273
PMCPMC6832870
OpenAlexW2957880587

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.