Evidence map›Paper›PMID 31298797›Full record

ReviewTraffic (Copenhagen, Denmark)2019

The structural biology of the dynamin-related proteins: New insights into a diverse, multitalented family.

Marijn G J Ford, Joshua S Chappie

Open access · bronzeAbstract readReview
In one paragraph

Review in Traffic (Copenhagen, Denmark), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. The trypanosomatid dynamin-like protein associates with glycosomes.bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. The dynamin-related proteinFrontiers in plant science · 2026
    Article
  6. Conformational Rearrangement of Fission DSPs.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  7. Structural and functional characterization of the brain-specific dynamin superfamily member RNF112.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Integrative modeling of guanylate binding protein dimers.Protein science : a publication of the Protein Society · 2023
    Article
  12. Article
  13. Article
  14. Mitochondrial Factors in the Cell Nucleus.International journal of molecular sciences · 2023
    Review
  15. Article
  16. Article
  17. Membrane fusion byMolecular biology of the cell · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Marijn G J FordDepartment of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.ORCID 0000-0002-9115-4413
Joshua S ChappieDepartment of Molecular Medicine, Cornell University, Ithaca, New York.ORCID 0000-0002-5733-7275
Cornell University · USUniversity of Pittsburgh · US

Funding

The Roles of the Dynamin-Related Protein Vps1 and the ESCRT Complex in MicroautophagyR01GM120102 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FORD, MARIJN GERARD JOHANNES · 2016 to 2020
$1.5M
NIGMS NIH HHS R01 GM120102
6 · The paper itself

Abstract

Dynamin-related proteins are multidomain, mechanochemical GTPases that self-assemble and orchestrate a wide array of cellular processes. Over the past decade, structural insights from X-ray crystallography and cryo-electron microscopy have reshaped our mechanistic understanding of these proteins. Here, we provide a historical perspective on these advances that highlights the structural attributes of different dynamin family members and explores how these characteristics affect GTP hydrolysis, conformational coupling and oligomerization. We also discuss a number of lingering challenges remaining in the field that suggest future directions of study.

Indexed as

AnimalsBinding SitesCryoelectron MicroscopyDynaminsGuanosine TriphosphateHumansMolecular Docking SimulationProtein BindingDynaminsGuanosine TriphosphateBSEbundle signaling elementdynamindynamin-related proteinsGTPasehelix

Identifiers

PMID31298797
PMCPMC6876869
OpenAlexW2961387473

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.