Evidence map›Paper›PMID 31298630›Full record

ArticleThyroid : official journal of the American Thyroid Association2019

Mouse Model of Thyroid Cancer Progression and Dedifferentiation Driven by STRN-ALK Expression and Loss of p53: Evidence for the Existence of Two Types of Poorly Differentiated Carcinoma.

Alyaksandr V Nikitski, Susan L Rominski, Vincenzo Condello, Cihan Kaya, Mamta Wankhede, Federica Panebianco, Hong Yang, Daniel L Altschuler, Yuri E Nikiforov

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Alyaksandr V NikitskiDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Susan L RominskiDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Vincenzo CondelloDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Cihan KayaDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Mamta WankhedeDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Federica PanebiancoDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Hong YangDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Daniel L AltschulerDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Yuri E NikiforovDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.
University of Pittsburgh · US

Funding

THYROID PHYSIOLOGY STUDIES OF INHERITED DISORDERSR01DK015070 · NIDDK · UNIVERSITY OF CHICAGO · PI ANTONIO C BIANCO, Alexandra Mihaela Dumitrescu · 1986 to 2026
$8.1M
THYROID PHYSIOLOGY STUDIES OF INHERITED DISORDERSR37DK015070 · NIDDK · UNIVERSITY OF CHICAGO · PI REFETOFF, SAMUEL · 1989 to 2015
$5.6M
ALK Rearrangements in Aggressive Thyroid CancerR01CA181150 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NIKIFOROV, YURI E · 2014 to 2024
$3.3M
NCI NIH HHS R01 CA181150NIDDK NIH HHS R01 DK015070NIDDK NIH HHS R37 DK015070
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anaplastic Lymphoma KinaseAnimalsAntithyroid AgentsCalmodulin-Binding ProteinsCell DedifferentiationCell DifferentiationDisease Models, AnimalDisease ProgressionMembrane ProteinsMethimazoleMiceMice, KnockoutMice, TransgenicNerve Tissue ProteinsOncogene Proteins, FusionPerchloratesAlk protein, mouseAnaplastic Lymphoma KinaseAntithyroid AgentsCalmodulin-Binding ProteinsMembrane ProteinsMethimazoleNerve Tissue ProteinsOncogene Proteins, FusionPerchloratesSodium CompoundsSodium-Iodide Symporterssodium perchlorateStrn protein, mouseSymportersThyroglobulinTrp53 protein, mouseTumor Suppressor Protein p53dedifferentiationp53poorly differentiated carcinomaSTRN-ALKthyroid cancer

Identifiers

PMID31298630
PMCPMC6797076
OpenAlexW2962222349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.