Evidence map›Paper›PMID 31298037›Full record

ArticleAIDS care2020

Barriers and facilitators to linkage to care and ART initiation in the setting of high ART coverage in Botswana.

Poloko Kebaabetswe, Kutlo Manyake, Etienne Kadima, Chloe Auletta-Young, Unoda Chakalisa, Tumalano Sekoto, Oarabile Makgabana Dintwa, Mompati Mmalane, Joseph Makhema, Refeletswe Lebelonyane and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in AIDS care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01965470 (Botswana Combination Prevention Project), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01965470 phase4completednot on this map

Botswana Combination Prevention Project: -Evaluation Protocol (Protocol #1): Research Design and Impact Evaluation -Closed Clinical Cohort Protocol (Protocol #3) Implementation, Monitoring and Evaluation of Combination HIV Prevention Interventions in Rural and Peri-Urban Communities in Botswana

TypeinterventionalSponsorCenters for Disease Control and PreventionRan2013 to 2018ConditionsHIVArmsCombination Prevention, Enhanced Care
3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  14. Causal Structural Learning on MPHIA Individual Dataset.Journal of the American Statistical Association · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Poloko KebaabetsweBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Kutlo ManyakeBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Etienne KadimaBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Chloe Auletta-YoungHarvard. T.H. Chan School of Public Health, Boston, MA, USA.
Unoda ChakalisaBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Tumalano SekotoBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Oarabile Makgabana DintwaBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Mompati MmalaneBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Joseph MakhemaBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Refeletswe LebelonyaneBotswana Ministry of Health and Wellness, Gaborone, Botswana.
Pamela BachanasCenters for Disease Control and Prevention, Atlanta, GA, USA.
Rebeca PlankHarvard. T.H. Chan School of Public Health, Boston, MA, USA.
Tendani GaolatheBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Shahin LockmanBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Molly Pretorius HolmeHarvard. T.H. Chan School of Public Health, Boston, MA, USA.

Funding

Mentoring in Patient-Oriented HIV Research in the Era of Universal ARTK24AI131928 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI SHAHIN LOCKMAN · 2017 to 2026
$1.9M
CGH CDC HHS U01 GH000447CGH CDC HHS U2G GH001911NIAID NIH HHS K24 AI131928
6 · The paper itself

Abstract

We conducted a qualitative study using focus groups and in-depth interviews to explore barriers to and facilitators of linkage-to-care and antiretroviral treatment (ART) initiation in Botswana. Participants were selected from communities receiving interventions through the Ya Tsie Study. Fifteen healthcare providers and 49 HIV-positive individuals participated. HIV-positive participants identified barriers including stigma, discrimination and overcrowded clinics, and negative staff attitudes; personal factors, such as a lack of acceptance of one's HIV status, non-disclosure, and gender differences; along with lack of social/family support, and certain religious beliefs. Healthcare providers cited delayed test results, poverty, and transport difficulties as additional barriers. Major facilitators were support from healthcare providers, including home visits, social support, and knowing the benefits of ART. Participants were highly supportive of universal ART as a personal health measure. Our results highlighted a persistent structural health facility barrier: HIV-positive patients expressed strong discontent with HIV care/treatment being delivered differently than routine healthcare, feeling inconvenienced and stigmatized by separately designated locations and days of service. This barrier was particularly problematic for highly mobile persons. Addressing this structural barrier, which persists even in the context of high ART uptake, could bring gains in willingness to initiate ART and improved adherence in Botswana and elsewhere.

Indexed as

HIV InfectionsAdultAnti-Retroviral AgentsBotswanaFemaleHumansMaleMiddle AgedQualitative ResearchSocial StigmaYoung AdultAnti-Retroviral Agentsantiretroviral initiationBarriersBotswanafacilitatorslinkage to HIV care

Identifiers

PMID31298037
PMCPMC6954979

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.