Evidence map›Paper›PMID 31298011›Full record

ReviewZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery2019

[Research progress in mesenchymal stem cells modified by Heme oxygenase 1].

Dong Sun, Hongli Song, Zhongyang Shen

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Dong SunThe First Central Clinical College, Tianjin Medical University, Tianjin, 300192, P.R.China.
Hongli SongDepartment of Organ Transplantation, Tianjin First Central Hospital, Tianjin Key Laboratory of Organ Transplantation, Key Laboratory of Transplantation Medicine, Chinese Academy of Medical Sciences, Tianjin, 300192, P.R.China.hlsong26@163.com.
Zhongyang ShenDepartment of Organ Transplantation, Tianjin First Central Hospital, Tianjin Key Laboratory of Organ Transplantation, Key Laboratory of Transplantation Medicine, Chinese Academy of Medical Sciences, Tianjin, 300192, P.R.China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNTianjin First Center Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo review the literature reports on research progress of Heme oxygenase 1 (HO-1) modified mesenchymal stem cells (MSCs).

methodsThe significance, effects, and related mechanism of HO-1 modification of MSCs were summarized by consulting the related literatures and reports of HO-1 modification of MSCs.

resultsHO-1 modification of MSCs has important research value. It can effectively enhance the anti-oxidative stress and anti-apoptotic properties of MSCs in complex internal environment after transplantation into vivo. It can also effectively enhance the immune regulation function of MSCs. It can improve the anti-injury, repair, and immune regulation effect of MSCs in various disease models and research fields.

conclusionThe basic research of HO-1 modified MSCs has made remarkable progress, which is expected to be applied in clinical trials and provide theoretical basis and reference value for stem cell therapy.

Indexed as

Heme Oxygenase-1Mesenchymal Stem CellsOxidative StressApoptosisResearchHeme Oxygenase-1anti-apoptosisHeme oxygenase 1immunoregulationMesenchymal stem cellsresearch progress

Identifiers

PMID31298011
PMCPMC8337431
OpenAlexW2996909569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.