Evidence map›Paper›PMID 31297972›Full record

ArticlePediatric obesity2019

Maternal blood pressure mediates the association between maternal obesity and infant weight gain in early postpartum.

Paige K Berger, Jasmine F Plows, Roshonda B Jones, Norman K Pollock, Tanya L Alderete, Ji Hoon Ryoo, Michael I Goran

Abstract read
In one paragraph

Article in Pediatric obesity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paige K BergerDepartment of Pediatrics, Children's Hospital Los Angeles, The University of Southern California, Los Angeles, CA, USA.ORCID 0000-0003-1670-5147
Jasmine F PlowsDepartment of Pediatrics, Children's Hospital Los Angeles, The University of Southern California, Los Angeles, CA, USA.
Roshonda B JonesDepartment of Pediatrics, Children's Hospital Los Angeles, The University of Southern California, Los Angeles, CA, USA.ORCID 0000-0003-1637-3517
Norman K PollockDepartment of Population Health Sciences, Medical College of Georgia, Augusta University, Augusta, GA, USA.ORCID 0000-0002-5465-2018
Tanya L AldereteDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.
Ji Hoon RyooDepartment of Pediatrics, Children's Hospital Los Angeles, The University of Southern California, Los Angeles, CA, USA.
Michael I GoranDepartment of Pediatrics, Children's Hospital Los Angeles, The University of Southern California, Los Angeles, CA, USA.

Funding

Impact of Sugars and Human Milk Oligosaccharides on Infant Microbiome and ObesityR01DK110793 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GORAN, MICHAEL ISAAC, PETERSON, BRADLEY S · 2017 to 2024
$6.0M
Near-Roadway and Ambient Air Pollution Exposure and the Gut Microbiome: Implications for Obesity and Insulin Resistance in AdolescenceR00ES027853 · NIEHS · UNIVERSITY OF COLORADO · PI ALDERETE, TANYA LYNN · 2018 to 2020
$721k
NIDDK NIH HHS NIH R01 DK110793NIDDK NIH HHS R01 DK110793NIEHS NIH HHS R00 ES027853The Gerber Foundation
6 · The paper itself

Abstract

backgroundIt is unknown to what extent higher maternal blood pressure (BP) in early postpartum impacts the relationship between higher maternal weight status and greater infant weight gain in early postpartum.

objectiveTo evaluate the mediating role of higher maternal BP at 1 month postpartum on the association between higher maternal weight status at 1 month postpartum and greater infant weight gain over 6 months postpartum.

methodsParticipants were 169 Hispanic mother-infant pairs. Maternal body mass index (BMI) and BP were assessed at 1 month postpartum. Infant weight was measured at 1 and 6 months postpartum to calculate weight-for-age z scores (WAZ). Multiple linear regression models were used for prediction, and Sobel test was used to determine mediation.

resultsControlling for maternal pre-pregnancy BMI, age, delivery mode, infant sex, and infant birth weight revealed that both maternal BMI (β = .29) and BP (β = .32) predicted infant WAZ gain (both P ≤ .03). However, the relationship between infant WAZ gain and maternal BMI was no longer significant after further adjustment for maternal BP, which remained significant (P < .05). Maternal BP explained 23.6% (Sobel T = 2.01) of the association between maternal BMI at 1 month and infant WAZ gain over 6 months.

conclusionOur data suggest that higher maternal weight status at 1 month postpartum is related to greater infant weight gain over 6 months postpartum, and this relationship is mediated by higher maternal BP at 1 month postpartum.

Indexed as

MothersAdultBirth WeightBlood PressureBody Mass IndexFemaleHispanic or LatinoHumansInfantLinear ModelsLos AngelesMaleMultivariate AnalysisPostpartum PeriodPregnancyPregnancy in Obesityblood pressureinfantmotherobesity

Identifiers

PMID31297972
PMCPMC6812591

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.