Evidence map›Paper›PMID 31297756›Full record

ReviewCurrent nutrition reports2019

The Endocrine Role of Bone in Cardiometabolic Health.

Rosemary DeLuccia, May Cheung, Rohit Ramadoss, Abeer Aljahdali, Deeptha Sukumar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current nutrition reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  4. Review
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  11. Low-Trauma Fracture Increases 12-Month Incidence of Cardiovascular Disease for Adults With Cerebral Palsy.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rosemary DeLucciaNutrition Sciences Department, Drexel University, Three Parkway Building Room 392, 1601 Cherry Street, Philadelphia, PA, 19102, USA.
May CheungNutrition Sciences Department, Drexel University, Three Parkway Building Room 392, 1601 Cherry Street, Philadelphia, PA, 19102, USA.
Rohit RamadossNutrition Sciences Department, Drexel University, Three Parkway Building Room 392, 1601 Cherry Street, Philadelphia, PA, 19102, USA.
Abeer AljahdaliNutrition Sciences Department, Drexel University, Three Parkway Building Room 392, 1601 Cherry Street, Philadelphia, PA, 19102, USA.
Deeptha SukumarNutrition Sciences Department, Drexel University, Three Parkway Building Room 392, 1601 Cherry Street, Philadelphia, PA, 19102, USA. deeptha.sukumar@drexel.edu.
Drexel University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to discuss the current knowledge about major bone regulating hormones vitamin D, parathyroid hormone (PTH), estrogen and bone metabolism markers osteocalcin (OC), bone-specific alkaline phosphatase (BAP), N-terminal propeptide of type 1 collagen (P1NP), and c-terminal type 1 collagen (CTX) and their mechanistic effects on cardiometabolic health. RECENT

findingsBone regulating hormones, nutrients, and turnover markers influence different aspects of cardiometabolic health including body composition, cardiovascular function, and glycemic control. While most observational research supports a relationship between bone as an endocrine organ and cardiometabolic outcomes, there are limited human clinical trials to strengthen a causal link between the two. While the associations between bone and cardiometabolic health are beginning to be understood based on findings from large observations studies, further exploration of bone's causal influence on health outcomes in humans and the underlying mechanisms of effect are necessary.

Indexed as

Alkaline PhosphataseBiomarkersBody CompositionBone and BonesBone RemodelingCardiovascular DiseasesCardiovascular SystemCollagen Type IEndocrine GlandsEstrogensGlycemic IndexHormonesHumansOsteocalcinParathyroid HormoneRisk FactorsAlkaline PhosphataseBiomarkersCollagen Type IEstrogensHormonesOsteocalcinParathyroid HormoneVitamin DBody compositionBoneBone turnoverCardiometabolic healthCardiovascular diseaseGlycemic control

Identifiers

PMID31297756
OpenAlexW2957715512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.