ArticleNeurocritical care2020
Dysautonomia in Guillain-Barré Syndrome: Prevalence, Clinical Spectrum, and Outcomes.
Article in Neurocritical care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05230641 (Cardiac Autonomic Dysfunction and Perioperative Outcomes After Neurosurgery), which is not on this map. Cited by 49 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cardiac Autonomic Dysfunction and Perioperative Outcomes After Neurosurgery
Who cites it
49 citing papers in PubMed, 121 citations in OpenAlex.
- Pediatric Guillain-Barré Syndrome Post Organ Transplant: Acute and Chronic Complication Requiring High Index of Suspicion.Pediatric transplantation · 2026Article
- Atypical Autonomic-Predominant Guillain-Barré Syndrome With Pandysautonomia Mimicking Parkinsonism and Recurrent Syncope: A Case Report.Clinical case reports · 2026Article
- Autonomic Dysfunction After Guillain-Barré Syndrome: Evidence from Comprehensive Autonomic Testing.Journal of clinical medicine · 2026Article
- Prognostic value of modified Erasmus Guillaiun Barre' syndrome outcome score (mEGOS) in an Italian cohort of patients: Challenges, insights and limitations.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Isolated Arterial Hypertension as a Rare Early Manifestation of Guillain-Barré Syndrome: A Case Report.Cureus · 2026Article
- Acute Urinary Retention and Guillain-Barré Syndrome: A Zebra or a Horse.Journal of the American College of Emergency Physicians open · 2026Article
- Fusion of molecular mimicry, epigenetic predisposition, and new onset GBS: a narrative review of current understanding and future directions.Annals of medicine and surgery (2012) · 2026Review
- Persistent autonomic dysfunction in a patient with Guillain-Barré syndrome following bariatric surgery.Acta neurologica Belgica · 2026Article
- Diagnosis and management of acute neuromuscular weakness.Singapore medical journal · 2026Article
- Atypical Presentation of Rapidly Progressive Guillain-Barré Syndrome With Dysautonomia in an Adolescent With PersistentCase reports in pediatrics · 2026Article
- Triple Vessel Disease With Intracranial Hemorrhage in a Patient With Guillain-Barre Syndrome: A Potential Complication, a Coincidental Finding or a Treatment-Related Adverse Event.Clinical case reports · 2025Article
- Pediatric Cardiac Arrest Secondary to Guillain-Barré Syndrome-Induced Dysautonomia.Children (Basel, Switzerland) · 2025Article
- Guillain-Barré Syndrome in Older People-A Case Report and Literature Review.Diseases (Basel, Switzerland) · 2025Review
- Guillain-Barré syndrome.BJA education · 2025Review
- A retrospective observational study of clinical and electrophysiological types of Guillain-Barre syndrome from Delhi.Journal of family medicine and primary care · 2025Article
- Critical insights for intensivists on Guillain-Barré syndrome.Annals of intensive care · 2025Review
- Clinical characteristics of Guillain-Barré syndrome in Shenzhen: a retrospective study.BMC neurology · 2025Article
- Association of dysautonomia and different risk factors in patients with Guillain-Barré syndrome in a tertiary hospital in the Philippines.BMC neurology · 2025Article
- Prognostic factors of mechanical ventilation in Guillain-Barré syndrome among adults and children in Vietnam.Clinical neurophysiology practice · 2025Article
- Clinical study of the relationship between hepatitis B core antibody and mechanical ventilation in patients with Guillain-Barré syndrome.Frontiers in neurology · 2025Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGuillain-Barré syndrome (GBS), when severe, involves the autonomic nervous system; our objective was to assess the spectrum and predictors of dysautonomia, and how it may impact functional outcomes.
methodsA retrospective review of patients admitted to the Mayo Clinic in Rochester, MN between January 1, 2000, and December 31, 2017, with GBS and dysautonomia was performed. Demographics, comorbidities, parameters of dysautonomia, clinical course, GBS disability score, and Erasmus GBS Outcome Score (EGOS) at discharge were recorded.
resultsOne hundred eighty seven patients were included with 71 (38%) noted to have at least one manifestation of dysautonomia. There are 72% of patients with a demyelinating form of GBS and 36% of patients with demyelination had dysautonomia. Ileus (42%), hypertension (39%), hypotension (37%), fever (29%), tachycardia or bradycardia (27%), and urinary retention (24%) were the most common features. Quadriparesis, bulbar and neck flexor weakness, and mechanical ventilation were associated with autonomic dysfunction. Patients with dysautonomia more commonly had cardiogenic complications, syndrome of inappropriate antidiuretic hormone, posterior reversible encephalopathy syndrome, and higher GBS disability score and EGOS. Mortality was 6% in patients with dysautonomia versus 2% in the entire cohort (P = 0.02).
conclusionsDysautonomia in GBS is a manifestation of more severe involvement of the peripheral nervous system. Accordingly, mortality and functional outcomes are worse. There is a need to investigate if more aggressive treatment is warranted in this category of GBS.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.