ReviewProtoplasma2019
Plant triterpenoid saponins: biosynthesis, in vitro production, and pharmacological relevance.
Review in Protoplasma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed.
- Growth Month-Associated Variation in Volatile Profiles, Anti-Glycation Capacity, and Antioxidant Activity ofFoods (Basel, Switzerland) · 2026Article
- Exploring the Chemical Profile and Biological Activities ofMolecules (Basel, Switzerland) · 2026Article
- Chromosome-level genome assembly of Tamarindus indica provides new insights into the evolution of triterpenes and tartaric acid biosynthetic pathway.Molecular horticulture · 2026Article
- Research progress on self-assembled supramolecular bioactive materials from herbal natural products and their applications in anti-infection field.Materials today. Bio · 2026Review
- Quantitative description and microscopic mechanism of ginsenosides' reactions during the thermal-driven processing of Panax ginseng.Journal of ginseng research · 2026Article
- Therapeutic Potential of Saikosaponins in MASLD and Cross-Organ Protection: A Research Update.Food science & nutrition · 2026Review
- Microbial consortia and their metabolic modulations as mechanisms of water deficit tolerance in strawberry plants.Frontiers in plant science · 2026Article
- Advancing the Potential ofMolecules (Basel, Switzerland) · 2025Review
- Plant-derived triterpenoid saponins: multifaceted roles and bioengineering prospects.Plant cell reports · 2025Review
- Telomere-to-telomere gap-free genome assembly provides genetic insight into the triterpenoid saponins biosynthesis inHorticulture research · 2025Article
- Methyl jasmonate induces the regulation of protostane triterpene biosynthesis by microRNAs in Alisma orientale.Protoplasma · 2025Article
- A Review of Phytochemical and Pharmacological Studies onMolecules (Basel, Switzerland) · 2025Review
- Rap1 overexpression boosts triterpenoid saponin production in yeast by enhancing precursor supply and heterologous gene expression.Microbial cell factories · 2025Article
- The emerging role of honeysuckle flower in inflammatory bowel disease.Frontiers in nutrition · 2025Review
- Food Functional Factors in Alzheimer's Disease Intervention: Current Research Progress.Nutrients · 2024Review
- Phytochemical Analysis and Antioxidant Activities of Various Extracts from the Aerial Part ofMolecules (Basel, Switzerland) · 2024Article
- Detection and Characterization of the Metabolites of Ciwujianoside B in Rats Based on UPLC-Fusion Lumos Orbitrap Mass Spectrometry.Journal of analytical methods in chemistry · 2024Article
- Full-length transcriptome characterization and comparative analysis of Gleditsia sinensis.BMC genomics · 2023Article
- Peculiarities of the Variation of Biologically Active Compounds in Fruit ofMolecules (Basel, Switzerland) · 2023Article
- Carrier-free nanoplatforms from natural plants for enhanced bioactivity.Journal of advanced research · 2023Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The saponins are a diverse class of natural products, with a broad scale distribution across different plant species. Chemically characterized as triterpenoid glycosides, they posses a 30C oxidosqualene precursor-based aglycone moiety (sapogenin), to which glycosyl residues are subsequently attached to yield the corresponding saponin. Based on the chemically distinct aglycone moieties, broadly, they are divided into triterpenoid saponins (dammaranes, ursanes, oleananes, lupanes, hopanes, etc.) and the sterol glycosides. This review aims to present in detail the biosynthesis patterns of the different aglycones from a common precursor and their glycosylation patterns to yield the functionally active glycoside. The review also presents recent advances in the pharmacological activities of these saponins, particularly as potent anti-neoplastic pharmacophores, antioxidants, or anti-viral/antibacterial agents. Since alternate production pedestals for these pharmacologically important triterpenes via cell and tissue cultures are an attractive option for their sustainable production, recent trends in the variety and scale of in vitro production of plant triterpenoids have also been discussed.
Indexed as
Identifiers
31297656What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.