Evidence map›Paper›PMID 31297628›Full record

ArticleWorld journal of urology2020

Management of patients with high-risk and advanced prostate cancer in the Middle East: resource-stratified consensus recommendations.

Deborah Mukherji, Bassem Youssef, Christelle Dagher, Albert El-Hajj, Rami Nasr, Fadi Geara, Danny Rabah, Saad Al Dousari, Rabih Said, Raja Ashou and 28 more

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in World journal of urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Trends of Prostate Cancer Morbidity in Low-Incidence Countries from 1990-2019.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. CACYBP knockdown inhibits progression of prostate cancer via p53.Journal of cancer research and clinical oncology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Prostate cancer management in the Middle East.World journal of urology · 2020
    Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 11 institutions in 6 countries.

Deborah MukherjiDivision of Hematology/Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, 1107 2020, Beirut, Lebanon. Dm25@aub.edu.lb.ORCID http://orcid.org/0000-0002-0192-5828
Bassem YoussefDepartment of Radiation Oncology, American University of Beirut Medical Center, Beirut, Lebanon.
Christelle DagherDivision of Hematology/Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, 1107 2020, Beirut, Lebanon.
Albert El-HajjDivision of Urology, Department of Surgery, American University of Beirut Medical Center, Riad El Solh, 1107 2020, Beirut, Lebanon.
Rami NasrDivision of Urology, Department of Surgery, American University of Beirut Medical Center, Riad El Solh, 1107 2020, Beirut, Lebanon.
Fadi GearaDepartment of Radiation Oncology, American University of Beirut Medical Center, Beirut, Lebanon.
Danny RabahDepartment of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Saad Al DousariDepartment of Surgery, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.
Rabih SaidDivision of Hematology/Oncology, Department of Internal Medicine, Saint Georges Hospital University Medical Center, Beirut, Lebanon.
Raja AshouDepartment of Radiology, Saint Georges Hospital University Medical Center, Beirut, Lebanon.
Wassim WazzanDepartment of Radiation Oncology, American University of Beirut Medical Center, Beirut, Lebanon.
Michel JabbourDivision of Urology, Department of Surgery, Saint Georges Hospital University Medical Center, Beirut, Lebanon.
George FarhaDepartment of Radiation Oncology, Mount Lebanon Hospital, Faculty of Medicine-University of Balamand, Beirut, Lebanon.
Nibras Al HamdaniDepartment of Surgery, Medical City Teaching Hospital Baghdad, Baghdad, Iraq.
Yousuf Al HallaqDepartment of Surgery, Medical City Teaching Hospital Baghdad, Baghdad, Iraq.
Hassan GhazalDivision of Hematology/Oncology, Department of Internal Medicine, Clemenceau Medical Center, Beirut, Lebanon.
Haifa DboukDivision of Oncology, Jamal Amel Hospital, Tyre, Lebanon.
Bassel BachirDepartment of Radiation Oncology, American University of Beirut Medical Center, Beirut, Lebanon.
Clement El KhouryDepartment of Radiation Oncology, Hotel Dieu de France, Saint Joseph University Faculty of Medicine, Beirut, Lebanon.
Ghazi SakrDivision of Urology, Department of Surgery, Mount Lebanon Hospital, Beirut, Lebanon.
Hero K HussainDepartment of Radiology, American University of Beirut Medical Center, Beirut, Lebanon.
Khaled SayyidDepartment of Surgery, Makassed Hospital, Beirut, Lebanon.
Khaled IbrahimDivision of Hematology/Oncology, Department of Internal Medicine, Hammoud Hospital University Medical Center, Saida, Lebanon.
Mohammad HaidarDepartment of Radiology, American University of Beirut Medical Center, Beirut, Lebanon.
Nicolas ZouainDepartment of Radiation Oncology, Clemenceau Medical Center, Beirut, Lebanon.
Nizar BitarDivision of Hematology/Oncology, Department of Internal Medicine, Sahel General Hospital, Beirut, Lebanon.
Walid AlamehDepartment of Surgery, Sahel General Hospital, Beirut, Lebanon.
Fadi AbbasMiddle East Tumor Institute, Beirut, Lebanon.
Sami FaddoulDoctors Center Radiology, Beirut, Lebanon.
Elie NemerDepartment of Urology, Saint Joseph University, Beirut, Lebanon.
Georges AssafDivision of Urology, Department of Surgery, Saint Georges Hospital University Medical Center, Beirut, Lebanon.
Fadi FarhatDivision of Hematology/Oncology, Department of Internal Medicine, Hammoud Hospital University Medical Center, Saida, Lebanon.
Muhammad BulbulDepartment of Radiation Oncology, American University of Beirut Medical Center, Beirut, Lebanon.
Sally TemrazDivision of Hematology/Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, 1107 2020, Beirut, Lebanon.
Ali ShamseddineDivision of Hematology/Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, 1107 2020, Beirut, Lebanon.
Silke GillessenDivision of Cancer Sciences, University of Manchester and the Christie, Manchester, UK.
Aurelius OmlinDepartment of Medical Oncology and Haematology, Cantonal Hospital Saint Gallen, University of Bern, Bern, Switzerland.
Raja KhauliDivision of Urology, Department of Surgery, American University of Beirut Medical Center, Riad El Solh, 1107 2020, Beirut, Lebanon. rkhauli@aub.edu.lb.
American University of Beirut Medical Center · LBSaint George Hospital · LBMakassed General Hospital · LBBaghdad Medical City · IQHammoud Hospital University Medical Center · LBSaint Joseph University · LBUniversity of Bern · CHKing Saud University · SAKuwait University · KWMiddle East University · LBUniversity of Balamand · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeProstate cancer care in the Middle East is highly variable and access to specialist multidisciplinary management is limited. Academic tertiary referral centers offer cutting-edge diagnosis and treatment; however, in many parts of the region, patients are managed by non-specialists with limited resources. Due to many factors including lack of awareness and lack of prostate-specific antigen (PSA) screening, a high percentage of men present with locally advanced and metastatic prostate cancer at diagnosis. The aim of these recommendations is to assist clinicians in managing patients with different levels of access to diagnostic and treatment modalities.

methodsThe first Advanced Prostate Cancer Consensus Conference (APCCC) satellite meeting for the Middle East was held in Beirut, Lebanon, November 2017. During this meeting a consortium of urologists, medical oncologists, radiation oncologist and imaging specialists practicing in Lebanon, Syria, Iraq, Kuwait and Saudi Arabia voted on a selection of consensus questions. An additional workshop to formulate resource-stratified consensus recommendations was held in March 2019.

resultsVariations in practice based on available resources have been proposed to form resource-stratified recommendations for imaging at diagnosis, initial management of localized prostate cancer requiring therapy, treatment of castration-sensitive/naïve advanced prostate cancer and treatment of castration-resistant prostate cancer.

conclusionThis is the first regional consensus on prostate cancer management from the Middle East. The following recommendations will be useful to urologists and oncologists practicing in all areas with limited access to specialist multi-disciplinary teams, diagnostic modalities and treatment resources.

Indexed as

Health ResourcesHealth Services AccessibilityProstatectomyRadiotherapy, AdjuvantAbiraterone AcetateAndrogen AntagonistsAntineoplastic AgentsAntineoplastic Agents, HormonalBenzamidesBiopsy, Large-Core NeedleBone NeoplasmsDocetaxelEndosonographyHumansIraqKallikreinsAbiraterone AcetateAndrogen AntagonistsAntineoplastic AgentsAntineoplastic Agents, HormonalBenzamidesDocetaxelenzalutamideKallikreinsKLK3 protein, humanNitrilesPhenylthiohydantoinProstate-Specific AntigenConsensusMiddle EastMultidisciplinaryProstate cancerResource-stratified recommendations

Identifiers

PMID31297628
PMCPMC7064460
OpenAlexW2958368309

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.