ArticleNorthern clinics of Istanbul2019
The relationship between caspase-1 related inflammasome expression and serum inflammatory cytokine levels during acute brucellosis.
Article in Northern clinics of Istanbul, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Intrauterine exposure to oxidative stress induces caspase-1-dependent enteric nerve cell pyroptosis.Pediatric surgery international · 2022Article
- Expression of NLRP3 and AIM2 inflammasome in Peripheral blood in Chinese patients with acute and chronic brucellosis.Scientific reports · 2022Article
- Influence of Lipoxin-A4 Treatment on Cytokine, Chemokine Genes Expression, and Phenotypic Distribution of Lymphocyte Subsets During Experimental Liver Fibrosis.The Eurasian journal of medicine · 2022Article
- Interplays between inflammasomes and viruses, bacteria (pathogenic and probiotic), yeasts and parasites.Immunology letters · 2020Review
- Immunological pathways of macrophage response toInnate immunity · 2020Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveBrucellosis is a zoonotic disease caused by
methodsPeripheral blood samples were obtained from 20 healthy volunteers and 20 patients with acute brucellosis. RNA and serum samples were isolated to examine the expression levels of
resultsIn the acute brucellosis group,
conclusionCaspase-1-related inflammasomes are sufficiently activated to induce the secretion of cytokines, such as IFN-γ and IL-18, to induce cellular immune response. Caspase-1 activation level should be investigated at different periods of disease in a group with high number of patients to understand the role of pyroptosis and caspase-1 in brucellosis.
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