ReviewCanadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR2019
High-frequency oscillatory ventilation: A narrative review.
Review in Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- High-frequency oscillatory ventilation with volume guarantee in infants: a systematic review.Pediatric research · 2025Pooled it
- Comparison of conventional mechanical ventilation and high-frequency oscillatory ventilation in congenital diaphragmatic hernias: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- The effect of NHFOV on hemodynamics in mild and moderately preterm neonates: a randomized clinical trial.European journal of pediatrics · 2024Trial
- Effect of high-frequency oscillation on reduction of atelectasis in perioperative patients: a prospective randomized controlled study.Annals of medicine · 2023Trial
- Using Dexcom G7 in Critically Ill Infant With Hyperinsulinemia on High Frequency Oscillatory Ventilation Support.HCA healthcare journal of medicine · 2025Article
- Gas transport mechanisms during high-frequency ventilation.Respiratory research · 2024Review
- High-Flow Oscillatory Ventilation: A Possible Therapeutic Option for Pediatric Patients with Cardiovascular Diseases.Pediatric reports · 2024Review
- Comparison of High-Frequency Oscillatory Ventilators.Respiratory care · 2024Article
- Pneumomediastinum and pneumothorax in acute respiratory distress syndrome (ARDS) patients: a narrative review.Mediastinum (Hong Kong, China) · 2024Review
- The effect of budesonide delivered by high-frequency oscillatory ventilation on acute inflammatory response in severe lung injury in adult rabbits.Physiological research · 2023Article
- Management of severe acute respiratory distress syndrome: a primer.Critical care (London, England) · 2023Review
- Pathophysiology of gas exchange impairment in extreme prematurity: Insights from combining volumetric capnography and measurements of ventilation/perfusion ratio.Frontiers in pediatrics · 2023Article
- Non-invasive high frequency oscillatory ventilation inhibiting respiratory motion in healthy volunteers.Scientific reports · 2022Article
- Piezoelectric Micromachined Ultrasonic Transducers (PMUTs): Performance Metrics, Advancements, and Applications.Sensors (Basel, Switzerland) · 2022Review
- An algorithm for difficult double lumen tube placement and troubleshooting a malpositioned double lumen tube harnessing A, B, Cs of lung isolation.Indian journal of anaesthesia · 2022Article
- Cardiopulmonary resuscitation of a very preterm infant using high-frequency oscillation ventilation.Resuscitation plus · 2022Article
- Electrical Impedance Tomography Can Be Used to Quantify Lung Hyperinflation during HFOV: The Pilot Study in Pigs.Diagnostics (Basel, Switzerland) · 2022Article
- Safety use of high frequency oscillatory ventilation in transport of newborn infants affected by severe respiratory failure: preliminary data in central Tuscany.BMC pediatrics · 2022Article
- Gas Exchange Mechanism of High Frequency Ventilation: A Brief Narrative Review and Prospect.Journal of Shanghai Jiaotong University (science) · 2022Article
- Examining lung mechanical strains as influenced by breathing volumes and rates using experimental digital image correlation.Respiratory research · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-frequency oscillatory ventilation (HFOV) is a lung-protective strategy that can be utilized in the full spectrum of patient populations ranging from neonatal to adults with acute lung injury. HFOV is often utilized as a rescue strategy when conventional mechanical ventilation (CV) has failed. HFOV uses low tidal volumes and constant mean airway pressures in conjunction with high respiratory rates to provide beneficial effects on oxygenation and ventilation, while eliminating the traumatic "inflate-deflate" cycle imposed by CV. Although statistical evidence supporting HFOV is particularly low, potential benefits for its application in many clinical manifestations still remain. High-frequency oscillation is a safe and effective rescue mode of ventilation for the treatment of acute respiratory distress syndrome (ARDS). All patients who have ventilator-induced lung injury (VILI) or are at risk of developing VILI or ARDS would be suitable candidates for HFOV, especially those who have failed conventional mechanical ventilation. This narrative aims to provide a review of HFOV vis-à-vis its indications, contraindications, hazards, parameters to monitoring, patient selection, clinical goals, mechanisms of action, controls for optimizing ventilation and oxygenation, clinical application in ARDS, and a comparison with other modes of mechanical ventilation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.