Evidence map›Paper›PMID 31297436›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)2019

Pharmaceutical company payments to the authors of the Japanese dementia clinical practice guidelines in 2016.

Yuki Shimada, Akihiko Ozaki, Hiroaki Saito, Toyoaki Sawano, Tetsuya Tanimoto

Abstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuki ShimadaDepartment of Neurosurgery, Minamisoma Municipal General Hospital, Minamisoma, Fukushima, Japan.
Akihiko OzakiMedical Governance Research Institute, Tokyo, Japan.
Hiroaki SaitoDepartment of Gastroenterology, Sendai Kousei Hospital, Sendai, Miyagi, Japan.
Toyoaki SawanoDepartment of Surgery, Minamisoma Municipal General Hospital, Minamisoma, Fukushima, Japan.
Tetsuya TanimotoMedical Governance Research Institute, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFinancial relationships between pharmaceutical companies and dementia clinical practice guideline (CPG) authors are possibly biasing the recommendations in Japan. This study aimed to reveal characteristics and distribution of pharmaceutical payments made to Japanese dementia CPG authors and an extent of the transparency in the conflicts of interest disclosure among them.

methodsWe retrospectively retrieved the publicly available data on payment to all the authors in the dementia CPGs by major pharmaceutical companies in Japan in 2016.

resultsThe total and mean payment values from pharmaceutical companies were $880,061 and $14,427, respectively. Of the 61 authors, 49 (80.3%) physicians received at least one payment. Financial relationships of the individual authors were not disclosed in the CPGs. DISCUSSION: Pharmaceutical companies with antidementia drugs had strong financial relationships with the CPG authors. To guarantee fairness in their relationships, it is imperative to establish a framework to disclose the corporate financial conflicts of interest.

Indexed as

Clinical practice guidelinesDementiaFinancial conflicts of interestJapanPharmaceutical payments

Identifiers

PMID31297436
PMCPMC6597934

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.