ArticleJournal of pharmaceutical analysis2019
Anticancer potential of metabolic compounds from marine actinomycetes isolated from Lagos Lagoon sediment.
Article in Journal of pharmaceutical analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- From antibiotic to antiviral: computational screening reveals a multi-targeting antibiotic from Streptomyces spp. against Nipah virus fusion proteins.Molecular diversity · 2025Article
- Biological activity of secondary metabolites of actinomycetes and their potential sources as antineoplastic drugs: a review.Frontiers in microbiology · 2025Review
- Actinomycetes: A Source of Anticancer Metabolites.Current medicinal chemistry · 2025Review
- Antioxidant and chemoprotective potential of Streptomyces levis strain isolated from human gut.AMB Express · 2023Article
- Screening of marine sediment-derived microorganisms and their bioactive metabolites: a review.World journal of microbiology & biotechnology · 2023Review
- Bioprospecting of desert actinobacteria with special emphases on griseoviridin, mitomycin C and a new bacterial metabolite producing Streptomyces sp. PU-KB10-4.BMC microbiology · 2023Article
- Analysis of the A549 cell line affected by anticancer bioactive compounds of Actinomycetes isolated from saline soils.Archives of microbiology · 2022Article
- Induction of apoptosis and cell cycle arrest in colorectal cancer cells by novel anticancer metabolites of Streptomyces sp. 801.Cancer cell international · 2022Article
- Characterization of Bioactive Actinomycetes Isolated from Kadolkele Mangrove Sediments, Sri Lanka.Polish journal of microbiology · 2022Article
- Marine Indole Alkaloids-Isolation, Structure and Bioactivities.Marine drugs · 2021Review
- Actinomycetes of secondary metabolite producers from mangrove sediments, Central Java, Indonesia.Veterinary world · 2021Article
- Novel Marine Secondary Metabolites Worthy of Development as Anticancer Agents: A Review.Molecules (Basel, Switzerland) · 2021Review
- Taxonomic and Metabolomics Profiling of Actinobacteria Strains from Himalayan Collection Sites in Pakistan.Current microbiology · 2021Article
- Bioprospecting marine actinomycetes for antileishmanial drugs: current perspectives and future prospects.Heliyon · 2021Review
- Isolation and characterization of marine sponge-associated Streptomyces sp. NMF6 strain producing secondary metabolite(s) possessing antimicrobial, antioxidant, anticancer, and antiviral activities.Journal, genetic engineering & biotechnology · 2021Article
- Marine Actinomycetes, New Sources of Biotechnological Products.Marine drugs · 2021Review
- Antimicrobial resistance in biofilms: Exploring marine actinobacteria as a potential source of antibiotics and biofilm inhibitors.Biotechnology reports (Amsterdam, Netherlands) · 2021Review
- Antifungal strains and gene mapping of secondary metabolites in mangrove sediments from Semarang city and Karimunjawa islands, Indonesia.AIMS microbiology · 2021Article
- Saccharomonosporine A inspiration; synthesis of potent analogues as potential PIM kinase inhibitors.RSC advances · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thirty-two actinomycetes strains were isolated from sediment samples from 12 different sites at Lagos Lagoon and identified using standard physiological and biochemical procedures as well as 16S rDNA gene sequence analysis. Secondary metabolites were extracted from the strains and their anticancer activity on the K562 (Human acute myelocytic leukemia), HeLa (cervical carcinoma), AGS (Human gastric), MCF-7 (breast adenocarcinoma) and HL-60 (Human acute promyelocytic leukemia) cell lines was determined. The metabolic extracts exhibited cytotoxicity with IC
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