Evidence map›Paper›PMID 31297270›Full record

ArticleCurrent health sciences journal

A Novel Method of Obtaining Platelet Rich Fibrin from Rats and Quantifying Platelet Count.

A F Grecu, D C Grecu, O Nica, E M Ciuca, A Camen, M E Ciurea

Abstract readCase Reports
In one paragraph

Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A F GrecuPhD Researcher, University of Medicine and Pharmacy of Craiova, Romania.
D C GrecuDepartment of Orthopaedic and Traumatology Surgery, University of Medicine and Pharmacy of Craiova, Romania.
O NicaPhD Researcher, University of Medicine and Pharmacy of Craiova, Romania.
E M CiucaDepartment of Oro-Maxilo-Facial Surgery, University of Medicine and Pharmacy of Craiova, Romania.
A CamenDepartment of Oro-Maxilo-Facial Surgery, University of Medicine and Pharmacy of Craiova, Romania.
M E CiureaDepartment of Plastic Surgery, University of Medicine and Pharmacy of Craiova, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesRat experimentation is the first line of research by which a medical hypothesis is usually tested. Platelet Rich Fibrin (PRF) is a relatively new bio-material that has shown promise to enhance healing in the field of bone research and tissue engineering. In order to perform PRF based experiments on rats, a proper protocol of obtaining PRF from rats needs to be established. MATERIALS AND

methods35 Wistar rats were used to obtain PRF by using cardiac puncture blood draw and quick subsequent centrifugation. The PRF samples wereanalyzed and compared to standard literature PRF composition.

resultsPRF samples analysis showed persistent results pertaining to known PRF composition.

conclusionsOur experiment has shown that our protocol of obtaining PRF is capable of providing high quality PRF from rats.

Indexed as

experimental animal modelsplatelet countPlatelet-rich fibrinproof of concept studytissue engineering

Identifiers

PMID31297270
PMCPMC6592675

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.