Evidence map›Paper›PMID 31297191›Full record

ArticleAntimicrobial resistance and infection control2019

Rapid screening and early precautions for carbapenem-resistant

Norihisa Yamamoto, Shigeto Hamaguchi, Yukihiro Akeda, Pitak Santanirand, Narong Chaihongsa, Suntariya Sirichot, Suwichak Chiaranaicharoen, Hideharu Hagiya, Kouji Yamamoto, Anusak Kerdsin and 6 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Antimicrobial resistance and infection control, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Update on infection prevention in the ICU.Current opinion in critical care · 2025
    Review
  2. Article
  3. Article
  4. Hospital Reservoirs of Multidrug ResistantBritish journal of biomedical science · 2023
    Review
  5. Control of Healthcare-Associated Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2022
    Article
  6. Article
  7. Article
  8. Carbapenem-resistantFrontiers in microbiology · 2022
    Review
  9. Detecting carbapenem-resistantInfection control and hospital epidemiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Norihisa Yamamoto1Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 Japan.
Shigeto Hamaguchi1Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 Japan.
Yukihiro Akeda1Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 Japan.
Pitak Santanirand3Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Narong Chaihongsa3Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Suntariya Sirichot3Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Suwichak Chiaranaicharoen3Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Hideharu Hagiya1Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 Japan.
Kouji Yamamoto4Department of Medical Statistics, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Anusak Kerdsin5Faculty of Public Health, Kasetsart University, Sakon Nakhon, Thailand.
Kazuhisa Okada2Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Hisao Yoshida1Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 Japan.
Shigeyuki Hamada2Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Kazunori Oishi6Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo, Japan.
Kumthorn Malathum3Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Kazunori Tomono1Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 Japan.
Osaka University · JPMahidol University · THNational Institute of Infectious Diseases · JPOsaka City University · JPRamathibodi Hospital · THSakon Nakhon Rajabhat University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Active surveillance has the potential to prevent nosocomial transmission of carbapenem-resistant Methods: A before and after (quasi-experimental) study was conducted in two ICUs at the Mahidol University Faculty of Medicine Ramathibodi Hospital with 3 months of observational period followed by 9 months of interventional period. All patients were screened for CRAB using both the culture and LAMP method from rectal swab and/or bronchial aspirates (intubated patients only) upon admission, weekly thereafter, and upon discharge. During the pre-intervention period, we performed contact precautions based on culture results. In contrast, during the intervention period, we initiated contact precautions within a few hours after sample collection on the basis of LAMP results. Results: A total of 1335 patients were admitted to the ICUs, of which 866 patients (pre-intervention period: 187; intervention period: 679) were eligible for this study. Incidence rate of CRAB infection decreased to 20.9 per 1000 patient-days in the intervention period from 35.2 in the pre-intervention period ( Conclusions: LAMP screening for CRAB upon ICU admission proved feasible for routine clinical practice. Rapid screening using LAMP followed by early intervention may reduce CRAB transmission rates in ICUs when compared to conventional intervention.

Indexed as

Drug Resistance, Multiple, BacterialAcinetobacter baumanniiAcinetobacter InfectionsAgedCarbapenemsCross InfectionEarly DiagnosisFemaleHumansIncidenceInfection ControlIntensive Care UnitsJapanMaleMiddle AgedMolecular Diagnostic TechniquesCarbapenemsCarbapenem-resistant Acinetobacter baumannii (CRAB)LAMP (Loop-mediated isothermal amplification), Rapid molecular diagnosis.Nosocomial transmissionRapid intervention, Intensive care unit.

Identifiers

PMID31297191
PMCPMC6598269
OpenAlexW2955078455

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.