ReviewF1000Research2019
Central sleep apnea: misunderstood and mistreated!
Review in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of acetazolamide on control of breathing in sleep apnea patients: Mechanistic insights using meta-analyses and physiological model simulations.Physiological reports · 2021Pooled it
- Physiology of lived experience: The struggles of my first experience of sleep at 3810 m.Experimental physiology · 2026Article
- Amyloid beta plaque pathology induces chemosensory deficits and increases apnoeas in the 5XFAD mouse model of Alzheimer's disease.The Journal of physiology · 2026Article
- Unraveling sleep apnea dynamics: quantifying loop gain using dynamical modeling of ventilatory control.Sleep · 2026Article
- Neonatal inflammation induces lasting sex- and region-dependent microglia activation and sex-dependent impairments in chemoreflexes.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Sleep-Disordered Breathing and Interactions with Opioids: A Narrative Review.Journal of clinical medicine · 2025Review
- Review
- Sleep-Disordered Breathing and Central Respiratory Control in Children: A Comprehensive Review.Children (Basel, Switzerland) · 2025Review
- The Prevalence of Central Sleep Apnea in New Referrals to a Sleep Surgery Clinic.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Observational
- Morphological Prediction of Continuous Positive Airway Pressure-associated Acute Respiratory Instability.Annals of the American Thoracic Society · 2025Article
- Long-Term Management of Sleep Apnea-Hypopnea Syndrome: Efficacy and Challenges of Continuous Positive Airway Pressure Therapy-A Narrative Review.Medical sciences (Basel, Switzerland) · 2024Review
- Altered control of breathing in a rat model of allergic lower airway inflammation.Journal of neurophysiology · 2024Article
- Obstructive Sleep Apnea after COVID-19: An Observational Study.Life (Basel, Switzerland) · 2024Article
- Central sleep apnoea: not just one phenotype.European respiratory review : an official journal of the European Respiratory Society · 2024Review
- Hypoxia Induces Alterations in the Circadian Rhythm in Patients with Chronic Respiratory Diseases.Cells · 2023Review
- Neuromedin B-Expressing Neurons in the Retrotrapezoid Nucleus Regulate Respiratory Homeostasis and Promote Stable Breathing in Adult Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Sleep Apnea and Substance Use Disorders Associated with Co-Occurrence of Anxiety Disorder and Depression among U.S. Adults: Findings from the NSDUH 2008-2014.Brain sciences · 2023Article
- Review
- A new approach to streamline obstructive sleep apnea therapy access using peripheral arterial tone-based home sleep test devices.Frontiers in sleep · 2023Article
- Revisiting the effects of the reciprocal function between alveolar ventilation and COJournal of applied physiology (Bethesda, Md. : 1985) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Central sleep apnea is prevalent in patients with heart failure, healthy individuals at high altitudes, and chronic opiate users and in the initiation of "mixed" (that is, central plus obstructive apneas). This brief review focuses on (a) the causes of repetitive, cyclical central apneas as mediated primarily through enhanced sensitivities in the respiratory control system and (b) treatment of central sleep apnea through modification of key components of neurochemical control as opposed to the current universal use of positive airway pressure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.