Evidence map›Paper›PMID 31297179›Full record

ArticleMolecular autism2019

Visual attention to faces in children with autism spectrum disorder: are there sex differences?

Clare Harrop, Desiree Jones, Shuting Zheng, Sallie Nowell, Robert Schultz, Julia Parish-Morris

Abstract read
In one paragraph

Article in Molecular autism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Eye Tracking as a Treatment Monitoring Tool for Autism: A Multilevel Meta-Analysis.Autism research : official journal of the International Society for Autism Research · 2025
    Pooled it
  2. Pooled it
  3. Gaze and social functioning associations in autism spectrum disorder: A systematic review and meta-analysis.Autism research : official journal of the International Society for Autism Research · 2022
    Pooled it
  4. Understanding the Effects of Naturalistic Developmental Behavioral Interventions: A Project AIM Meta-analysis.Autism research : official journal of the International Society for Autism Research · 2021
    Pooled it
  5. Diametrically opposed sex-specific effects of autistic traits on risk-taking in poker.PCN reports : psychiatry and clinical neurosciences · 2026
    Article
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  9. Relations Between Preferential Looking to Synchronous Audiovisual Speech and Expressive Language in Infants With Autistic and Non-Autistic Siblings.Mind, brain and education : the official journal of the International Mind, Brain, and Education Society · 2026
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  16. Cognitive flexibility in autism: How task predictability and sex influence performances.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  17. Article
  18. Are the diagnostic rates of autistic females increasing? An examination of state-wide trends.Journal of child psychology and psychiatry, and allied disciplines · 2024
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Clare Harrop1University of North Carolina at Chapel Hill, Allied Health Sciences, Bondurant Hall, Chapel Hill, NC 27599 USA.ORCID 0000-0003-3381-3473
Desiree Jones2School of Behavioral and Brain Sciences, University of Texas-Dallas, Richardson, TX 75080 USA.
Shuting Zheng3STAR Center for ASD and NDDs, University of California San Francisco, San Francisco, CA 94143 USA.
Sallie Nowell4Frank Porter Graham Child Development Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 USA.
Robert SchultzCenter for Autism Research, Children's Hospital of Philadelphia, Roberts Center for Pediatric Research, Philadelphia, PA 19146 USA.
Julia Parish-MorrisCenter for Autism Research, Children's Hospital of Philadelphia, Roberts Center for Pediatric Research, Philadelphia, PA 19146 USA.

Funding

North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
UNC MRDD Research CenterP30HD003110 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BELGER, AYSENIL · 1985 to 2012
$28.7M
The Intellectual and Developmental Disabilities Research Center at CHOP/PennU54HD086984 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI PUTT, MARY E. · 2016 to 2020
$6.3M
Behavioral Inflexibility in IDD Outcome MeasurementR01HD082127 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOYD, BRIAN ANTONIO · 2015 to 2019
$2.8M
NCATS NIH HHS UL1 TR001111NICHD NIH HHS P30 HD003110NICHD NIH HHS R01 HD082127NICHD NIH HHS U54 HD086984
6 · The paper itself

Abstract

Background: The male bias in autism spectrum disorder (ASD) diagnoses is well documented. As a result, less is known about the female ASD phenotype. Recent research suggests that conclusions drawn from predominantly male samples may not accurately capture female behavior. In this study, we explore potential sex differences in attention to social stimuli, which is generally reported to be diminished in ASD. Population-based sex differences in attention to faces have been reported, such that typically developing (TD) females attend more to social stimuli (including faces) from infancy through adulthood than TD males. It is yet unknown whether population-based sex differences in the face domain are preserved in ASD. Methods: A dynamic, naturalistic infrared eye-tracking paradigm measured attention to social stimuli (faces) in 74 school-aged males and females with ASD (male Results: Results revealed a significant 3-way interaction between sex, diagnosis, and condition after controlling for chronological and mental age. ASD females attended more to faces than ASD males in the socially lean condition. This effect was not found in the typically developing (TD) group. ASD males attended less to faces regardless of social context; however, ASD females only attended significantly less to faces compared to TD females in the socially rich condition. TD males and ASD females did not differ in their attention to faces in either condition. Conclusions: This study has implications for how the field understands core social deficits in children with ASD, which should ideally be benchmarked against same-sex peers (male and female). Social attention in ASD females fell on a continuum-greater than their ASD male peers, but not as great as TD females. Overall, their social attention mirrored that of TD males. Improved understanding of the female social phenotype in ASD will enhance early screening and diagnostic efforts and will guide the development of sex-sensitive experimental paradigms and social interventions.

Indexed as

AttentionSex CharacteristicsAutism Spectrum DisorderChildFacial RecognitionFemaleFixation, OcularHumansMalePhotic StimulationAutism spectrum disorderEye gazeSex differencesSocial attentionSocial cognition

Identifiers

PMID31297179
PMCPMC6599259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.