Evidence map›Paper›PMID 31297159›Full record

ArticleBiotechnology for biofuels2019

Overcoming cellulose recalcitrance in woody biomass for the lignin-first biorefinery.

Haibing Yang, Ximing Zhang, Hao Luo, Baoyuan Liu, Tânia M Shiga, Xu Li, Jeong Im Kim, Peter Rubinelli, Jonathan C Overton, Varun Subramanyam and 10 more

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 96 citations in OpenAlex.

  1. Article
  2. Enhancing monolignol ferulate conjugate levels in poplar lignin via OsFMT1.Biotechnology for biofuels and bioproducts · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Redesigning plant cell walls for the biomass-based bioeconomy.The Journal of biological chemistry · 2020
    Review
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 1 country.

Haibing Yang1Department of Biological Sciences, Purdue University, West Lafayette, IN 47907 USA.
Ximing Zhang2Laboratory of Renewable Resource Engineering (LORRE), Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907 USA.
Hao Luo3Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA 93106 USA.
Baoyuan Liu3Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA 93106 USA.
Tânia M Shiga4Department of Botany and Plant Pathology, Purdue University, West Lafayette, IN 47907 USA.
Xu Li5Department of Biochemistry, Purdue University, West Lafayette, IN 47907 USA.
Jeong Im Kim5Department of Biochemistry, Purdue University, West Lafayette, IN 47907 USA.
Peter Rubinelli6Department of Forestry and Natural Resources, Purdue University, West Lafayette, IN 47907 USA.
Jonathan C Overton2Laboratory of Renewable Resource Engineering (LORRE), Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907 USA.
Varun Subramanyam4Department of Botany and Plant Pathology, Purdue University, West Lafayette, IN 47907 USA.
Bruce R Cooper7Bindley Bioscience Center, Purdue University, West Lafayette, IN 47907 USA.
Huaping Mo8Department of Chemistry, Purdue University, West Lafayette, IN 47907 USA.
Mahdi M Abu-Omar3Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA 93106 USA.
Clint Chapple4Department of Botany and Plant Pathology, Purdue University, West Lafayette, IN 47907 USA.
Bryon S DonohoeNational Renewable Energy Laboratory, Biosciences Center, Golden, CO 80401 USA.
Lee Makowski10Department of Bioengineering, Northeastern University, Boston, MA 02115 USA.
Nathan S Mosier2Laboratory of Renewable Resource Engineering (LORRE), Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907 USA.
Maureen C McCann1Department of Biological Sciences, Purdue University, West Lafayette, IN 47907 USA.
Nicholas C Carpita1Department of Biological Sciences, Purdue University, West Lafayette, IN 47907 USA.
Richard Meilan6Department of Forestry and Natural Resources, Purdue University, West Lafayette, IN 47907 USA.
Purdue University West Lafayette · USUniversity of California, Santa Barbara · USNational Renewable Energy Laboratory · USNortheastern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow-temperature swelling of cotton linter cellulose and subsequent gelatinization in trifluoroacetic acid (TFA) greatly enhance rates of enzymatic digestion or maleic acid-AlCl

resultsLow-temperature (- 20 °C) treatment of S-lignin-rich poplar wood particles in TFA slightly increased yields of glucose from enzymatic digestions and HMF and LA from maleic acid-AlCl

conclusionsGenetic modification of lignin composition can enhance the portfolio of aromatic products obtained from lignocellulosic biomass while promoting disassembly into biofuel and bioproduct substrates. CDL enhances rates of enzymatic digestion and chemical conversion, but cellulose remains intrinsically recalcitrant. Cold TFA is sufficient to overcome this recalcitrance after CDL treatment. Our results inform a 'no carbon left behind' strategy to convert total woody biomass into lignin, cellulose, and hemicellulose value streams for the future biorefinery.

Indexed as

CatalysisCelluloseDelignificationLigninPoplarRecalcitrance

Identifiers

PMID31297159
PMCPMC6599248
OpenAlexW2954548860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.