Evidence map›Paper›PMID 31297155›Full record

ReviewBiotechnology for biofuels2019

Butanol production from lignocellulosic biomass: revisiting fermentation performance indicators with exploratory data analysis.

Cansu Birgen, Peter Dürre, Heinz A Preisig, Alexander Wentzel

Abstract readReview
In one paragraph

Review in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Toxic Effects of Butanol in the Plane of the Cell Membrane.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  2. Article
  3. COFrontiers in bioengineering and biotechnology · 2024
    Article
  4. Review
  5. Biobutanol production from underutilized substrates usingCurrent research in microbial sciences · 2024
    Review
  6. Sustainable production of biofuels from the algae-derived biomass.Bioprocess and biosystems engineering · 2023
    Article
  7. Advances in biosynthesis of higher alcohols in Escherichia coli.World journal of microbiology & biotechnology · 2023
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Modulation ofFrontiers in genetics · 2022
    Article
  13. Renewable Butanol Production via Catalytic Routes.International journal of environmental research and public health · 2021
    Review
  14. Review
  15. Article
  16. Article
  17. Genetic sensor-regulators functional in Clostridia.Journal of industrial microbiology & biotechnology · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cansu Birgen1Department of Chemical Engineering, NTNU, 7491 Trondheim, Norway.ORCID 0000-0002-8176-6758
Peter Dürre2Institute of Microbiology and Biotechnology, Ulm University, 89069 Ulm, Germany.
Heinz A Preisig1Department of Chemical Engineering, NTNU, 7491 Trondheim, Norway.
Alexander WentzelSINTEF Industry, 7465 Trondheim, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After just more than 100 years of history of industrial acetone-butanol-ethanol (ABE) fermentation, patented by Weizmann in the UK in 1915, butanol is again today considered a promising biofuel alternative based on several advantages compared to the more established biofuels ethanol and methanol. Large-scale fermentative production of butanol, however, still suffers from high substrate cost and low product titers and selectivity. There have been great advances the last decades to tackle these problems. However, understanding the fermentation process variables and their interconnectedness with a holistic view of the current scientific state-of-the-art is lacking to a great extent. To illustrate the benefits of such a comprehensive approach, we have developed a dataset by collecting data from 175 fermentations of lignocellulosic biomass and mixed sugars to produce butanol that reported during the past three decades of scientific literature and performed an exploratory data analysis to map current trends and bottlenecks. This review presents the results of this exploratory data analysis as well as main features of fermentative butanol production from lignocellulosic biomass with a focus on performance indicators as a useful tool to guide further research and development in the field towards more profitable butanol manufacturing for biofuel applications in the future.

Indexed as

ABE fermentationButanolClostridiaExploratory data analysisLignocellulosic biomassMixed sugars

Identifiers

PMID31297155
PMCPMC6598312

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.