Evidence map›Paper›PMID 31297130›Full record

ArticleFrontiers in genetics2019

Nicole Ziliotto, Giovanna Marchetti, Chiara Scapoli, Matteo Bovolenta, Silvia Meneghetti, Andrea Benazzo, Barbara Lunghi, Dario Balestra, Lorenza Anna Laino, Nicolò Bozzini and 7 more

Abstract read
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. WWOX Loss of Function in Neurodevelopmental and Neurodegenerative Disorders.International journal of molecular sciences · 2020
    Review
  11. "International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Nicole ZiliottoDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Giovanna MarchettiDepartment of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.
Chiara ScapoliDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Matteo BovolentaDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Silvia MeneghettiDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Andrea BenazzoDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Barbara LunghiDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Dario BalestraDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Lorenza Anna LainoDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Nicolò BozziniDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Irene GuidiDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Fabrizio SalviIRCCS Institute of Neurological Sciences, Hospital Bellaria, Bologna, Italy.
Sofia StraudiDepartment of Neurosciences and Rehabilitation, S. Anna University Hospital, Ferrara, Italy.
Donato GemmatiDepartment of Biomedical & Specialty Surgical Sciences and Centre Haemostasis & Thrombosis, Section of Medical Biochemistry, Molecular Biology & Genetics, University of Ferrara, Ferrara, Italy.
Erica MenegattiDepartment of Morphology, Surgery and Experimental Medicine, Vascular Diseases Center, University of Ferrara, Ferrara, Italy.
Paolo ZamboniDepartment of Morphology, Surgery and Experimental Medicine, Vascular Diseases Center, University of Ferrara, Ferrara, Italy.
Francesco BernardiDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In light of the complex nature of multiple sclerosis (MS) and the recently estimated contribution of low-frequency variants into disease, decoding its genetic risk components requires novel variant prioritization strategies. We selected, by reviewing MS Genome Wide Association Studies (GWAS), 107 candidate loci marked by intragenic single nucleotide polymorphisms (SNPs) with a remarkable association (

Indexed as

C6orf10low-frequency variantsmultiple sclerosisrare variantswhole exome sequencing

Identifiers

PMID31297130
PMCPMC6607989

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.