Evidence map›Paper›PMID 31296864›Full record

ArticleNature communications2019

Eradication of unresectable liver metastasis through induction of tumour specific energy depletion.

Da Huo, Jianfeng Zhu, Guojun Chen, Qian Chen, Chao Zhang, Xingyu Luo, Wei Jiang, Xiqun Jiang, Zhen Gu, Yong Hu

Abstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Combating VEGFA-siRNA-Induced Metabolic Reprogramming via Glucose Utilization Deprivation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Da HuoCollaborative Innovation Center of Chemistry for Life Sciences, College of Engineering and Applied Sciences, Nanjing University, Nanjing, Jiangsu, China.
Jianfeng ZhuCollaborative Innovation Center of Chemistry for Life Sciences, College of Engineering and Applied Sciences, Nanjing University, Nanjing, Jiangsu, China.
Guojun ChenDepartment of Bioengineering and the California Nanosystems Institute, University of California, Los Angeles, CA, USA.
Qian ChenDepartment of Bioengineering and the California Nanosystems Institute, University of California, Los Angeles, CA, USA.
Chao ZhangCollaborative Innovation Center of Chemistry for Life Sciences, College of Engineering and Applied Sciences, Nanjing University, Nanjing, Jiangsu, China.
Xingyu LuoCollaborative Innovation Center of Chemistry for Life Sciences, College of Engineering and Applied Sciences, Nanjing University, Nanjing, Jiangsu, China.
Wei JiangCollaborative Innovation Center of Chemistry for Life Sciences, College of Engineering and Applied Sciences, Nanjing University, Nanjing, Jiangsu, China.
Xiqun JiangDepartment of Polymer Science & Engineering, College of Chemistry & Chemical Engineering, Nanjing University, Nanjing, Jiangsu, China. jiangx@nju.edu.cn.ORCID http://orcid.org/0000-0003-0483-0282
Zhen GuDepartment of Bioengineering and the California Nanosystems Institute, University of California, Los Angeles, CA, USA. guzhen@ucla.edu.ORCID http://orcid.org/0000-0003-2947-4456
Yong HuCollaborative Innovation Center of Chemistry for Life Sciences, College of Engineering and Applied Sciences, Nanjing University, Nanjing, Jiangsu, China. hvyong@nju.edu.cn.ORCID http://orcid.org/0000-0002-5394-6743

Funding

National Natural Science Foundation of China (National Science Foundation of China) 21474047National Natural Science Foundation of China (National Science Foundation of China) 81371516National Natural Science Foundation of China (National Science Foundation of China) 81671751
6 · The paper itself

Abstract

Treatment of liver metastasis experiences slow progress owing to the severe side effects. In this study, we demonstrate a strategy capable of eliminating metastatic cancer cells in a selective manner. Nucleus-targeting W

Indexed as

AnimalsCathepsin BCell NucleusDrug CarriersFemaleHCT116 CellsHepatocytesHumansInjections, IntravenousLasersLiverLiver NeoplasmsMiceMice, Inbred BALB CMice, NudeMitochondriaCathepsin BCTSB protein, humanDrug CarriersOxidesPhotosensitizing AgentsReactive Oxygen SpeciesSilicon DioxideTungstentungsten oxide

Identifiers

PMID31296864
PMCPMC6624273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.