ArticleScience (New York, N.Y.)2019
Posterior parietal cortex plays a causal role in perceptual and categorical decisions.
Article in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
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Who cites it
76 citing papers in PubMed.
- Posterior parietal cortex mediates rarity-induced decision bias.National science review · 2026Article
- Distinct directional patterns of somatosensory interhemispheric interactions in expert pianists and nonmusicians.iScience · 2026Article
- Frontal Eye Field Leads a Distributed Oculomotor Circuit for Abstract Categorical Decisions.bioRxiv : the preprint server for biology · 2026Article
- Distinct sources of decision-related signals in visual cortex are represented in different local field potential bands.PLoS biology · 2026Article
- Neural Responses to Affective Sentences Reveal Signatures of Depression.Translational psychiatry · 2026Article
- Single-neuron network topology governs neural computation and learning in primate cortex.Nature communications · 2026Article
- Time-resolved EEG decoding reveals altered neural dynamics of affective semantic evaluation in depression and suicidality.Communications biology · 2026Article
- Evolutionarily old brainstem neurons are required for the control of selective spatial attention.Nature communications · 2026Article
- Augmentation of frontoparietal gamma-band phase coupling enhances human altruistic behavior.PLoS biology · 2026Article
- Occipital and parietal non-invasive brain stimulation enhances perceptual learning and transfer: evidence from high-frequency tRNS.Frontiers in neuroscience · 2026Article
- Parietal cortex is causally required for state-dependent decisions.Cell reports · 2025Article
- Identifying the factors governing internal state switches during nonstationary sensory decision-making.Nature communications · 2025Article
- Neural correlates of trial outcome monitoring during long-term learning in primate posterior parietal cortex.Nature communications · 2025Article
- Nonlinear feedback modulation contributes to the optimization of flexible decision-making.eLife · 2025Article
- Parietal cortex is causally required for state-dependent decisions.bioRxiv : the preprint server for biology · 2025Article
- Anatomical circuits for flexible spatial mapping by single neurons in posterior parietal cortex.Communications biology · 2025Article
- Time-adaptive modulation of evidence evaluation in rat posterior parietal cortex.bioRxiv : the preprint server for biology · 2025Article
- Target Selection Signals Causally Influence Human Perceptual Decision-Making.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Distinct neural population code and causal roles of primate caudate nucleus in multimodal decision-making.Nature communications · 2025Article
- Locomotion-dependent auditory gating to the parietal cortex guides multisensory decisions.Nature communications · 2025Article
16 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
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Abstract
Posterior parietal cortex (PPC) activity correlates with monkeys' decisions during visual discrimination and categorization tasks. However, recent work has questioned whether decision-correlated PPC activity plays a causal role in such decisions. That study focused on PPC's contribution to motor aspects of decisions (deciding where to move), but not sensory evaluation aspects (deciding what you are looking at). We employed reversible inactivation to compare PPC's contributions to motor and sensory aspects of decisions. Inactivation affected both aspects of behavior, but preferentially impaired decisions when visual stimuli, rather than motor response targets, were in the inactivated visual field. This demonstrates a causal role for PPC in decision-making, with preferential involvement in evaluating attended task-relevant sensory stimuli compared with motor planning.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.